HLTH 237 Ch. 1-4 Flashcards

1
Q

What are psychoactive drugs?

A

Natural or synthesized substances that alter the central and autonomic nervous systems, affecting thoughts, emotions, and behaviors. They can balance or disrupt biological functions and may be medical or non-medical, licit or illicit.

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2
Q

What is drug misuse, and what are its consequences?

A

Occasional improper or inappropriate use of drugs (social or prescription), leading to adverse effects like medical complications, behavioral alterations, social and legal problems, and potential addiction or dependence

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3
Q

How does the American Society of Addiction Medicine (ASAM) define addiction?

A
  • A treatable, chronic medical disease involving complex brain circuits, genetics, environment, and life experiences.
  • People with addiction use substances or engage in behaviors compulsively despite harmful consequences.
  • Treatment and prevention are as effective as for other chronic diseases.
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4
Q

How was addiction conceptualized historically?

A
  • Focused on morality and workplace productivity.
  • Viewed addiction as a behavioral issue involving compulsive drug-seeking, loss of control, and lifestyle breakdown.
  • Abstinence was seen as the only solution.
  • Linked to physical withdrawal symptoms in the 1950s–60
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5
Q

How did the WHO redefine addiction in 1964?

A

The WHO broadened the concept to “dependence,” recognizing both physical and psychological components of addiction.

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6
Q

What are the criticisms of the ASAM definition of addiction?

A
  • Focuses narrowly on the medical aspects of addiction.
  • Does not include the holistic nature of addiction, which involves social, economic, and situational factors.
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7
Q

How do social scientists view addiction beyond its medical aspects?

A
  • Stanton Peele: Addiction is not solely chemical but a social experience that creates dependency on particular states of mind and body.
  • Anthropologists and human geographers emphasize the cultural and contextual aspects of substance use (e.g., social settings and timing).
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8
Q

What are the conditions for addiction, according to Peele and Brodsky?

A
  • Readily available substances.
  • Severe stress (e.g., misery, danger, discomfort).
  • Alienation.
  • Emotional or vocational deprivation.
  • Lack of control over one’s life.
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9
Q

What did studies on U.S. soldiers in Vietnam reveal about addiction?

A
  • 75% of soldiers who used heroin in Vietnam reported addiction.
  • Only one-third continued use after returning to the U.S., and only 10% showed dependency.
  • Highlights the importance of social and environmental factors in addiction.
    *
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9
Q

Why is addiction considered a bio-psycho-social phenomenon?

A
  • Addiction involves biological factors (brain circuits, genetics), psychological factors (stress, coping mechanisms), and social factors (environment, relationships).
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10
Q

What are the two main types of drug dependency?

A
  • Physical Dependency: The body adapts to the drug, leading to withdrawal symptoms if use stops.
  • Psychological Dependency: The drug becomes central to thoughts and actions, often more significant than physical dependency.
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11
Q

Why aren’t eating disorders considered addictions?

A
  • Dopamine release from eating is insufficient for addiction-like reinforcement compared to drugs.
  • Tolerance and withdrawal are not consistently demonstrated.
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11
Q

What behaviors or conditions are often mistaken for addiction?

A
  • Behaviors without distinct biological or chemically induced changes (e.g., compulsive eating or gambling).
  • Conditions lacking evidence of tolerance, withdrawal, or nervous system changes caused by psychoactive substances.
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12
Q

How is gambling classified in addiction research?

A
  • DSM-V: Substance-related disorder.
  • WHO ICD-11: Impulse control disorder.
  • Gambling shares characteristics with addiction (e.g., impulsivity, decision-making deficits) but lacks a biological trigger or withdrawal effects
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12
Q

What are the four main drug groups?

A
  1. Depressants: Reduce CNS activity (e.g., alcohol, benzodiazepines).
  2. Stimulants: Increase CNS activity, elevate mood, and increase alertness (e.g., caffeine, amphetamines).
  3. Hallucinogens: Disrupt perception, cognition, and mood (e.g., LSD, cannabis).
  4. Psychotherapeutic Agents: Treat mental health disorders (e.g., antidepressants, antipsychotics)a
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13
Q

Why is “sex addiction” not considered a true addiction?

A
  • Evidence-based research does not support “sex addiction” as a distinct addiction.
  • Classified as a compulsive or impulsive behavior rather than an addiction.
  • No chemical or biological basis as seen in substance addiction.
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14
Q

What are the effects and uses of depressants?

A
  • Effects: Reduction in CNS arousal and activity.
  • Uses: As anesthetics, sleep aids, anti-anxiety agents, and sedatives.
  • Examples: Alcohol, benzodiazepines, opioids.
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15
Q

How do hallucinogens affect the brain?

A

Hallucinogens cause a generalized disruption in brain processes, altering perception, cognition, and mood. Cannabis is a hallucinogen but acts more like a depressant.

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15
Q

What are the effects and common uses of stimulants?

A
  • Effects: Elevate mood, increase vigilance, and postpone fatigue.
  • Uses: Treat ADHD, suppress appetite, and relieve nasal congestion.
  • Examples: Cocaine, amphetamines, caffeine.
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16
Q

What are psychotherapeutic agents, and why are they less likely to be misused?

A
  • Definition: Drugs primarily used to treat mental health issues like depression, bipolar disorder, and psychosis.
  • Misuse: Less likely because they aren’t rapidly acting and often cause unpleasant side effects.
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17
Q

Why is dopamine significant in drug use and addiction?

A

Dopamine stimulates brain nerves, creating sensations of power, energy, and euphoria. Most drugs of misuse increase dopamine activity, reinforcing addictive behavior.

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17
Q

What are neurotransmitters, and where are they found?

A

Chemicals in the brain that relay, amplify, and modulate signals between neurons. They are found in the synaptic cleft.

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18
Q

How does THC interact with the brain?

A

THC binds with receptors in the brain, causing euphoria, time distortion, and mild hallucinogenic effects. It also increases dopamine release.

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19
Q

What is the role of endorphins in the brain?

A

Endorphins bind to opioid receptors, blocking pain and modulating dopamine transmission, which can lead to euphoria.

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20
Q

How do GABA and glutamate function in the brain?

A
  • GABA: Inhibitory neurotransmitter that calms the brain and reduces anxiety.
  • Glutamate: Excitatory neurotransmitter linked to memory and learning. It balances GABA’s effects.
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21
Q

What is serotonin’s role in mental health?

A

Known as the “happiness transmitter,” serotonin reduces depression, alleviates anxiety, and elevates mood

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22
Q

How does norepinephrine influence the body?

A

Active in the fight-or-flight response.
High levels can cause anxiety and mania.
Inhibiting norepinephrine can alleviate depression.

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23
Q

What is pharmacodynamics?

A

The study of what drugs do to the body, including their mechanisms of action, tolerance, and withdrawal effects.

24
Q

What are the different types of tolerance?

A
  • Dispositional:The liver processes drugs more efficiently.
    * Functional: Changes in receptors reduce drug sensitivity.
  • Cross-Tolerance:Tolerance to one drug leads to reduced sensitivity to another with similar effects.
  • Tachyphylaxis:Rapid development of tolerance.
25
Q

What is reverse tolerance (sensitization)?

A

A condition where less of a drug is needed to achieve the desired effect, often due to heightened sensitivity in the brain.

26
Q

What is withdrawal in the context of pharmacodynamics?

A

The physical or psychological symptoms that occur when drug use is abruptly stopped, often opposite to the drug’s effects.

27
Q

What is pharmacokinetics?

A

The study of how drugs are absorbed, distributed, metabolized, and excreted in the body.

28
Q

What are the main routes of drug administration?

A
  • Oral:Convenient but slow absorption.
  • Injection: Quick effect but high overdose risk.
  • Inhalation: Rapid onset but lung damage.
    * Transdermal: Convenient but limited recreational use.
  • Mucous Membrane: Quick but can cause tissue damage.
29
Q

What are the advantages and disadvantages of oral drug administration?

A
  • Advantages: Easy and convenient.
  • Disadvantages: Slow absorption, potential for stomach discomfort, and difficulty in calculating the absorbed dose.
30
Q

Why is injection a common route for drug administration, and what are the risks?

A

Benefits: Quick effect and accurate dosing.
Risks: Overdose, pain, and disease transmission from shared needles.

31
Q

What are the pros and cons of inhalation and transdermal drug administration?

A
  • Inhalation: Quick effect but can damage lungs.
  • Transdermal: Convenient but limited to certain drugs and uses.
32
Q

What are the global trends in alcohol use?

A
  • 1/3 of the world consumes alcohol, with use 10 times higher than illicit drugs.
  • Europe has the highest consumption rates, while North African and Middle Eastern countries have the lowest.
  • Alcohol-related premature deaths decreased globally from 1990 to 2017, except in the U.S. and Russia.
32
Q

How has global drug use changed between 1990 and 2016?

A

There has been an overall increase in drug use worldwide.

32
Q

What percentage of the global adult population uses psychoactive drugs, and how many use illegal drugs?

A
  • 50% of adults use psychoactive drugs regularly.
  • 5.5% used illegal drugs in the previous year.
33
Q

What are the key statistics for alcohol use in Canada?

A
  • 78% of Canadians aged 15+ consumed alcohol in the last year.
  • 21% of drinkers exceeded low-risk drinking guidelines.
33
Q

How has illicit drug use changed in Canada since the 1990s?

A
  • Increased from 1% of the population in the 1990s to 3% in 2017.
  • The greatest rise has been in opioid-related toxicity events and cocaine use.
33
Q

Why is cannabis significant in global drug use?

A

Cannabis is the most widely used illicit drug worldwide.

33
Q

What are the key statistics for tobacco use globally?

A
  • 1.1 billion people use tobacco, with 80% residing in developing countries.
  • Tobacco contributes the most to the global disease burden, causing 8 million deaths annually, including 1.2 million from secondhand smoke.
34
Q

How has tobacco use in Canada changed over time?

A
  • Cigarette use dropped from 50% in 1965 to 15% today.
  • E-cigarettes are used by 23% of youth (ages 15–19) and 29% of young adults (ages 20–24).
35
Q

What percentage of Canadians use prescription psychoactive drugs, and which group uses them more?

A
  • 22% of people aged 15+ use prescription psychoactive drugs.
  • Women use them more than men.
36
Q

What are the trends in cannabis use in Canada?

A
  • Recreational use rose from 5.5% in 1985 to 15% in 2014.
  • Lifetime use is 41.5%.
  • Legalization in 2019 increased use by only 2% (from 14.8% to 16.8%).
36
Q

What are the major economic costs of psychoactive drug use?

A

Costs include healthcare expenses, law enforcement efforts, lost productivity, and the burden on individuals and society.

37
Q

What are the alcohol use trends among Canadian students in grades 7–12?

A

44% consumed alcohol at least once in the past year.
Regular use is less common but increases with age.

37
Q

How prevalent is e-cigarette use among Canadian students?

A

20% of students in grades 7–12 have used e-cigarettes.
Has gone up since time of writing

38
Q

Which drug contributes the most to the global disease burden?

A

Tobacco, with 8 million annual deaths and widespread health consequences.

38
Q

Has cannabis legalization increased its use in Canada?

A

No significant increase; use rose only 2% after legalization.

39
Q

How does substance use vary by region globally?

A
  • Europe: Highest alcohol use.
  • North America: Highest opioid and amphetamine use.
  • Middle East and North Africa: Lowest alcohol use.
39
Q

How have alcohol-related deaths changed globally?

A

Premature deaths from alcohol use have decreased worldwide except in the U.S. and Russia

40
Q

hat are the key principles of the moral model of addiction?

A
  • Drug use is considered unacceptable, wrong, or sinful.
  • Addiction results from personal choice and moral failings.
  • Individuals are solely responsible for their behavior and can decide not to use substances.
41
Q

How does the moral model contribute to stigma around addiction?

A
  • Labels people with addiction as having deep character flaws.
  • Promotes blame and shame, making it easier to reject or ignore those struggling with substance use.
42
Q

How does the language of the moral model affect perceptions of drug users?

A

Negative language reinforces societal rejection and dehumanizes people with addiction, making them easier to discard or blame.

42
Q

What were the outcomes of the War on Drugs?

A
  • No significant reduction in illicit or licit drug use.
  • Increased incarceration rates, especially among minorities.
  • Focused on punishment rather than treatment or harm reduction.
42
Q

How does the moral model view personal responsibility in addiction?

A

It asserts that people with addiction can choose to stop using drugs and that their behavior reflects a lack of willpower or character.

43
Q

What does the moral model fail to recognize about addiction?

A

It ignores the complex biological, psychological, and social factors that contribute to addiction, such as brain chemistry, trauma, and socioeconomic influences.

43
Q

What were the key components of the War on Drugs in the U.S.?

A
  • Began in the 1970s under Nixon and intensified in the 1980s with Reagan.
  • Involved military enforcement, mandatory minimum sentences, and the death penalty for drug “kingpins.”
  • Led to mass incarceration, particularly targeting marginalized racial and socioeconomic groups.
44
Q

How was the War on Drugs implemented outside the U.S.?

A
  • Canada: Less pronounced but included attempts at mandatory minimums, later struck down by courts.
  • The Philippines: Duterte’s administration allowed military and paramilitary groups to kill suspected drug dealers and users, resulting in over 22,000 deaths.
  • Vietnam, Cambodia, and China: Forced work camps for drug users.
45
Q

How prevalent is the death penalty for drug offenses worldwide?

A

By 2020, 66% of countries with the death penalty had laws applying it to drug-related offenses.

46
Q

What are the major criticisms of the moral model?

A
  • Overemphasizes personal choice, ignoring external factors like environment and genetics.
  • Fails to support empirical evidence of addiction as a bio-psycho-social phenomenon.
  • Stigmatizes individuals, reducing access to compassionate treatment.
47
Q

How do alternative models challenge the moral model of addiction?

A
  • Medical Model:Addiction is a chronic disease requiring treatment.
  • Social Models: Emphasize the role of environmental, economic, and social factors in addiction.
  • * Holistic Models:Incorporate biological, psychological, and social elements for a comprehensive understanding.
47
Q

Why does the moral model label addiction as a moral failing?

A

It views addiction as a result of weak character, lack of willpower, and poor moral choices, rather than a condition influenced by complex factors.

48
Q

According to the moral model, what is the “solution” to addiction?

A

Addiction is solved through personal willpower, determination, and removal from temptation, without the need for medical or social interventions.

49
Q

How does alcohol present inconsistencies in the moral model?

A

In Western countries, alcohol is legal and socially accepted, complicating the moral stance that all drug use is inherently wrong.

50
Q

What backlash has harm reduction faced due to the moral model?

A

The moral model opposes harm reduction efforts like safe injection sites and needle exchange programs, framing them as enabling drug use rather than addressing its causes.

51
Q

Why does the moral model oppose social reforms to address addiction?

A

The model relies on individual accountability and rejects systemic solutions, such as addressing poverty, inequality, or access to healthcare, as irrelevant to addiction.