HLTH 237 Ch. 1-4 Flashcards
What are psychoactive drugs?
Natural or synthesized substances that alter the central and autonomic nervous systems, affecting thoughts, emotions, and behaviors. They can balance or disrupt biological functions and may be medical or non-medical, licit or illicit.
What is drug misuse, and what are its consequences?
Occasional improper or inappropriate use of drugs (social or prescription), leading to adverse effects like medical complications, behavioral alterations, social and legal problems, and potential addiction or dependence
How does the American Society of Addiction Medicine (ASAM) define addiction?
- A treatable, chronic medical disease involving complex brain circuits, genetics, environment, and life experiences.
- People with addiction use substances or engage in behaviors compulsively despite harmful consequences.
- Treatment and prevention are as effective as for other chronic diseases.
How was addiction conceptualized historically?
- Focused on morality and workplace productivity.
- Viewed addiction as a behavioral issue involving compulsive drug-seeking, loss of control, and lifestyle breakdown.
- Abstinence was seen as the only solution.
- Linked to physical withdrawal symptoms in the 1950s–60
How did the WHO redefine addiction in 1964?
The WHO broadened the concept to “dependence,” recognizing both physical and psychological components of addiction.
What are the criticisms of the ASAM definition of addiction?
- Focuses narrowly on the medical aspects of addiction.
- Does not include the holistic nature of addiction, which involves social, economic, and situational factors.
How do social scientists view addiction beyond its medical aspects?
- Stanton Peele: Addiction is not solely chemical but a social experience that creates dependency on particular states of mind and body.
- Anthropologists and human geographers emphasize the cultural and contextual aspects of substance use (e.g., social settings and timing).
What are the conditions for addiction, according to Peele and Brodsky?
- Readily available substances.
- Severe stress (e.g., misery, danger, discomfort).
- Alienation.
- Emotional or vocational deprivation.
- Lack of control over one’s life.
What did studies on U.S. soldiers in Vietnam reveal about addiction?
- 75% of soldiers who used heroin in Vietnam reported addiction.
- Only one-third continued use after returning to the U.S., and only 10% showed dependency.
- Highlights the importance of social and environmental factors in addiction.
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Why is addiction considered a bio-psycho-social phenomenon?
- Addiction involves biological factors (brain circuits, genetics), psychological factors (stress, coping mechanisms), and social factors (environment, relationships).
What are the two main types of drug dependency?
- Physical Dependency: The body adapts to the drug, leading to withdrawal symptoms if use stops.
- Psychological Dependency: The drug becomes central to thoughts and actions, often more significant than physical dependency.
Why aren’t eating disorders considered addictions?
- Dopamine release from eating is insufficient for addiction-like reinforcement compared to drugs.
- Tolerance and withdrawal are not consistently demonstrated.
What behaviors or conditions are often mistaken for addiction?
- Behaviors without distinct biological or chemically induced changes (e.g., compulsive eating or gambling).
- Conditions lacking evidence of tolerance, withdrawal, or nervous system changes caused by psychoactive substances.
How is gambling classified in addiction research?
- DSM-V: Substance-related disorder.
- WHO ICD-11: Impulse control disorder.
- Gambling shares characteristics with addiction (e.g., impulsivity, decision-making deficits) but lacks a biological trigger or withdrawal effects
What are the four main drug groups?
- Depressants: Reduce CNS activity (e.g., alcohol, benzodiazepines).
- Stimulants: Increase CNS activity, elevate mood, and increase alertness (e.g., caffeine, amphetamines).
- Hallucinogens: Disrupt perception, cognition, and mood (e.g., LSD, cannabis).
- Psychotherapeutic Agents: Treat mental health disorders (e.g., antidepressants, antipsychotics)a
Why is “sex addiction” not considered a true addiction?
- Evidence-based research does not support “sex addiction” as a distinct addiction.
- Classified as a compulsive or impulsive behavior rather than an addiction.
- No chemical or biological basis as seen in substance addiction.
What are the effects and uses of depressants?
- Effects: Reduction in CNS arousal and activity.
- Uses: As anesthetics, sleep aids, anti-anxiety agents, and sedatives.
- Examples: Alcohol, benzodiazepines, opioids.
How do hallucinogens affect the brain?
Hallucinogens cause a generalized disruption in brain processes, altering perception, cognition, and mood. Cannabis is a hallucinogen but acts more like a depressant.
What are the effects and common uses of stimulants?
- Effects: Elevate mood, increase vigilance, and postpone fatigue.
- Uses: Treat ADHD, suppress appetite, and relieve nasal congestion.
- Examples: Cocaine, amphetamines, caffeine.
What are psychotherapeutic agents, and why are they less likely to be misused?
- Definition: Drugs primarily used to treat mental health issues like depression, bipolar disorder, and psychosis.
- Misuse: Less likely because they aren’t rapidly acting and often cause unpleasant side effects.
Why is dopamine significant in drug use and addiction?
Dopamine stimulates brain nerves, creating sensations of power, energy, and euphoria. Most drugs of misuse increase dopamine activity, reinforcing addictive behavior.
What are neurotransmitters, and where are they found?
Chemicals in the brain that relay, amplify, and modulate signals between neurons. They are found in the synaptic cleft.
How does THC interact with the brain?
THC binds with receptors in the brain, causing euphoria, time distortion, and mild hallucinogenic effects. It also increases dopamine release.
What is the role of endorphins in the brain?
Endorphins bind to opioid receptors, blocking pain and modulating dopamine transmission, which can lead to euphoria.
How do GABA and glutamate function in the brain?
- GABA: Inhibitory neurotransmitter that calms the brain and reduces anxiety.
- Glutamate: Excitatory neurotransmitter linked to memory and learning. It balances GABA’s effects.
What is serotonin’s role in mental health?
Known as the “happiness transmitter,” serotonin reduces depression, alleviates anxiety, and elevates mood
How does norepinephrine influence the body?
Active in the fight-or-flight response.
High levels can cause anxiety and mania.
Inhibiting norepinephrine can alleviate depression.