History Of Microbiology Flashcards

1
Q

Were the first to record observations of microbes through simple microscope.

A

Robert Hooke and Antoni van Leeuwenhoek

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2
Q

Who showed that microbes arise from preexisting microbes and demonstrated heat sterilization?

A

Lazaro Spallanzani

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3
Q

Who used the gooseneck flask experiment to disprove spontaneous generation?

A

Louis Pasteur

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4
Q

Who developed heat canning?

A

Nicholas Appert

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5
Q

Who devised techniques of pure culture to study single species of microbes in isolation?

A

Robert Koch

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6
Q

What provides a set of criteria to establish a causative link between an infectious agent and a disease?

A

Koch’s postulates

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7
Q

Who established the practice of vaccination, inoculation of cowpox to prevent smallpox?

A

Edward Jenner

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8
Q

Who developed the first vaccine based on attenuated strains, such as the rabies vaccine?

A

Louis Pasteur

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9
Q

Who showed that hand washing and antiseptic could prevent transmission of pathogens from doctor to patient?

A

Ignaz Semmelweis and Joseph Lister

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10
Q

Who discovered that penicillum mold generated a substance that kills bacteria?

A

Alexander Fleming

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11
Q

Who purified the substance penicillin to create an antibiotic to save human lives?

A

Howard Florey and Ernest Chain

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12
Q

Who developed a system of enrichment culture, Winogradsky column, to grow microbes from natural environments?

A

Sergei Winogradsky

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13
Q

Who demonstrated that nitrogen-fixing rhizobia grow as endosymbiosis within leguminous plants?

A

Martinis Beijerinck

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14
Q

Who recognized that microbes constitute a form of life distinct from animals and plants?

A

Ernest Haeckel

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15
Q

Who classified prokaryotes as a form of microbial life distinct from eukaryotic microbes such as protists?

A

Herbert Copeland and Robert Whittaker

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16
Q

Who discovered a domain of prokaryotes, Archea, whose genetic sequence diverge equally from those of bacteria and those of eukaryotes?

A

Carl Woese