HISTOPATH Flashcards
4 MAJOR DEVELOPMENTAL DEFECTS
Agenesia
Atresia
Hypoplasia
Aplasia
2 Types of Cell Injury
Reversible Injury
Irreversible Injury
Causes of Cell Injury
Oxygen deprivation
physical, biological, mechanical agents
7 cellular adaptations mechanisms.
HHAMDAN
Atrophy
Hypertrophy
Hyperplasia
Metaplasia
Anaplasia
Dysplasia
Neoplasia
Types Of Biopsies
Excisional
Incisional
Fine needle aspiration
Types of Necrosis
Coagulative
Liquefactive
Caseous
Fat
Fibrinoid
necrosis Seen in acute pancreatitis, necrotic material appears
like chalky white precipitate
Fat necrosis
In situ dissection
done in its original place
C. Rokitansky
En – bloc removal of organs
A. Ghon
Adequate Fixation pH
Between 6-8
Temperature to Accelerate
Fixation
37-56 °C
Routine Fixative
10% NBF (Neutral Buffered Formalin)
Nuclear Fixatives
Carnoy’s, Bouin’s, Newcomer’s, Heidenhain’s Susa, Flemming’s
Cytoplasmic Fixatives:
Regaud’s/Muller’s, Orth’s, Formalin with post chroming Flemming’s
without Hac (Acetic Acid)
% Glutaraldehyde - for small tissue fragments/needle biopsies
2.5% Glutaraldehyde