CC practice test Flashcards
Which of the following conditions
is most consistently associated
with hypercholesterolemia?
A. Hypothyroidism
B. Malabsorption syndrome
C. Pancreatitis
D. Diabetes mellitus
Hypothyroidism
When using the Friedewald
equation to estimate LDL
cholesterol, the error becomes
unacceptably high at triglyceride
levels:
A. <200 mg/dL
B. >200 mg/dL
C. <400 mg/dL
D. >400 mg/dL
> 400 mg/dL
. A patient’s total cholesterol is 300
mg/dL, his HDL cholesterol is 50
mg/dL, and his triglyceride is 200
mg/dL. What is this patient’s LDL
cholesterol when calculated using
the Friedewald equation?
A. 200
B. 210
C. 290
D. 350
210
A fluorometer uses a secondary
monochromator to isolate the
wavelength emitted by the
A. gas discharge lamp
B. atomizer
C. ground-state atoms
D. excited molecules
excited molecules
Which lipoprotein is associated
with obstructive biliary disease
and familial LCAT deficiency?
A. B-VLDL
B. LpX
C. Lp(a)
D. LDL
LpX
Deficiency of which of the
following apolipoproteins causes
reduced clearance of triglyceriderich lipoproteins?
A. B-48
B. A-IV
C. C-II
D. Apo(a)
B-48
As part of a routine physical, a
fasting plasma glucose is
performed on a 45-year-old male
and the test result is 105 mg/dL.
How should this individual be
classified?
A. Normal for his age
B. Impaired fasting glucose
C. Type 1 diabetes mellitus
D. Type 2 diabetes mellitus
Impaired fasting glucose
What is the reference method for
non-protein nitrogenous
compounds?
A. GCMS
B. Tandem MS
C. MALDI TOF
D. IDMS
IDMS
Cigarette smoking will cause
falsely increased result in the
following methods for urea
EXCEPT:
A. Nesslerization
B. Berthelot
C. Conductimetric
D. Diacetyl monoxime
Diacetyl monoxime
Which of the following is the
common initial reaction in the
enzymatic methods for
creatinine?
A. Hydrolysis of creatinine
B. Hydrolysis of creatine
C. Phosphorylation of creatine
D. Oxidation of sarcosine
Hydrolysis of creatinine
Which of the following is
measured in the creatininase–CK
coupled?
A. Increased absorbance of
NADH at 340 nm
B. Decreased absorbance of
NAD at 340 nm
C. Increase in color intensity
of the oxidized chromogen
D. Decrease in color intensity
of the oxidized chromogen
Decreased absorbance of
NAD at 340 nm
Which of the following would be
consistent with pre-renal
azotemia?
A. BUN/Creatinine ratio >20:1
with normal creatinine
B. BUN/Creatinine ratio >20:1
with elevated creatinine
C. BUN/Creatinine ratio <10:1
D. Increased creatinine
clearance
BUN/Creatinine ratio >20:1
with normal creatinine
Dyes used in serum protein
electrophoresis include the
following EXCEPT:
A. Ponceau S
B. Amido black
C. Coomassie blue
D. Bromcresol green
Bromcresol green
Which of the following is
associated with
hyperalbuminemia?
A. Malnutrition
B. Nephrotic syndrome
C. Liver disease
D. Dehydration
Dehydration
Which of the following are α2-
globulins?
1. Haptoglobin
2. Inter-α-trypsin inhibitor
3. Ceruloplasmin
4. α-fetoprotein
A. 1 and 3
B. 2 and 4
C. 1, 2, and 3
1 and 3
In iron deficiency anemia, serum
iron and transferrin are
respectively:
A. Decreased, increased
B. Increased, decreased
C. Decreased, decreased
D. Increased, increased
Decreased, increased
if a hemolyzed serum is used in
electrophoresis, an additional
band will be seen between:
A. β and γ zones
B. α2 and β1 zones
C. α1 and α2 zones
D. β1 and β2 zones
α2 and β1 zones
What is the characteristic
densitometric pattern associated
with hepatic cirrhosis?
A. α1 and α2 peaks
B. sharp γ peak
C. β-γ bridging
D. α1 flat curve
β-γ bridging
Which of the following is used as
a negative predictor of myocardial
infarction within the first 4 hours?
A. hsCRP
B. Myoglobin
C. Troponin I
D. Homocysteine
Myoglobin
The following proteins are used to
evaluate glomerular filtration rate
EXCEPT:
A. Cystatin C
B. β2-microglobulin
C. β Trace Protein
D. Atrial natriuretic peptide
Atrial natriuretic peptide
Which of the following represents
proteolytic fragments of collagen I and is used as a biochemical
marker of bone resorption?
A. Neuronal Thread Protein
B. Cross-linked C Telopeptide
C. Amyloid β42
D. Atrial natriuretic peptide
Cross-linked C Telopeptide
Which of the following is the
ultimate reference method for
protein based on the
measurement of nitrogen
content?
A. Kjeldahl method
B. Biuret method
C. Folin-Ciocalteau (Lowry)
method
D. Ninhydrin method
Kjeldahl method
A BUN result of 15 mg/dL is
obtained by a technologist. What
is the equivalent urea
concentration?
A. 32.1 mg/dL
B. 5.36 mg/dL
C. 2.5 mg/dL
D. 3.21 mg/dL
32.1 mg/dL
Which of the following are positive
acute-phase reactants?
1. α1-antitrypsin
2. Haptoglobin
3. C-reactive protein
4. Fibrinogen
A. 1 and 3
B. 2 and 4
C. 1, 2, and 3
D. 1, 2, 3, and 4
1, 2, 3, and 4
What clinical manifestation would
be consistent with a densitometric
pattern that shows a marked
decrease in the α1-globulin peak
area?
A. Pulmonary emphysema
B. Acute inflammation
C. Nephrotic syndrome
D. Agammaglobulinemia
Pulmonary emphysema
Which of the following light
sources is used in atomic
absorption spectrophotometry?
A. Hollow-cathode lamp
B. Xenon Arc Lamp
C. Tungsten Light
D. Deuterium Lamp
Hollow-cathode lamp
Which of the following represents
an enzyme’s catalytic
mechanism?
A. E + S → ES → E → P
B. E + P → EP → E → S
C. E + S + P → ESP
D. ESP → E + S + P
E + S → ES → E → P
Which of the following is NOT
associated with pronounced AST
elevation?
A. Acute hepatocellular
disorders
B. Circulatory collapse
C. Myocardial infarction
D. Biliary obstruction
Biliary obstruction
Which of the following enzyme
assays is subject to end product
inhibition by inorganic
phosphorus?
A. Forward LD
B. Reverse CK
C. GGT
D. ALP
ALP
What is the substrate used in the
Bowers-McComb assay?
A. α-naphthylphosphate
B. β-glycerophosphate
C. phenylphosphate
D. p-nitrophenylphosphate
p-nitrophenylphosphate
Increased sodium loss in urine
can occur with the following
conditions, EXCEPT:
A. Addison’s disease
B. Salt-losing nephropathy
C. Renal failure
D. Thiazide diuretic use
Renal failure
Which of the following is the most
routinely used method for serum
sodium determination?
A. AAS
B. FEP
C. ISE
D. Albanese-Lein
ISE
High serum chloride values are
associated with:
A. Prolonged vomiting
B. Diabetic ketoacidosis
C. Compensated respiratory
acidosis
D. Metabolic acidosis
Metabolic acidosis
What do the following results
suggest?
Serum calcium – elevated;
serum inorganic
phosphate – decreased;
urine calcium – elevated;
urine
inorganic phosphate – elevated
A. Hypovitaminosis D
B. Paget disease
C. Renal failure
D. Hyperparathyroidism
Hyperparathyroidism
What is the reagent used in the
Fiske-Subbarow method?
A. o-cresolphthalein
complexone
B. Arsenazo III
C. 8-hydroxyquinoline
D. Ammonium molybdate
Ammonium molybdate
Which of the following conditions
is associated with
hypophosphatemia?
A. Lymphoblastic leukemia
B. Vitamin D deficiency
C. Renal failure
D. Intravascular hemolysis
Vitamin D deficiency
Calculate the plasma osmolality
given the following information:
glucose – 124 mg/dL; BUN – 22
mg/dL; sodium – 138 mmol/L;
potassium – 5 mmol/L; chloride –
105 mmol/L; bicarbonate – 25
mmol/L.
A. 13 mmol/L
B. 13 mOsm/kg
C. 290 mOsm/kg
D. 290 mmol/L
290 mOsm/kg
Low anion gap may be caused by:
A. Decreased unmeasured
cations and increased
unmeasured anions
B. Increased unmeasured
cations and anions
C. Increased unmeasured
cations and decreased
unmeasured anions
D. Decreased unmeasured
cations and anions
Increased unmeasured
cations and decreased
unmeasured anions
The ratio of HCO3 and H2CO3
may be decreased by:
A. An increase in the
reclamation of HCO3
B. A decrease in pulmonary
ventilation
C. A decrease in the excretion
of HCO3
D. An increase in the rate of
respiration
A decrease in pulmonary
ventilation
Which of the following is the
compensatory mechanism in
respiratory acidosis?
A. Decreased renal
production of ammonia
B. Decreased bicarbonate
reabsorption
C. Increased CO2 retention
D. Increased bicarbonate
retention
Increased bicarbonate
retention