Histology of muscle Flashcards

1
Q

What are the two myofilaments?

A

Thick filament
Thin filament

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2
Q

What is the primary component of thick filaments?

A

Myosin II

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3
Q

What is the primary component of thin filaments?

A

Actin

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4
Q

What is a sarcolemma?

A

Muscle cell membrane

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5
Q

What is sarcoplasm?

A

Cytoplasm of a muscle cell

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6
Q

What are sarcosomes?

A

Muscle cell mitochondria

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7
Q

What is sarcoplasmic reticulum?

A

Muscle cell ER

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8
Q

What are the three CTs found in skeletal muscle?

A

Epimysium
Perimysium
Endomysium

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9
Q

What is the role epimysium?

A

Separates gross muscle into fascicles

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10
Q

What is the role of perimysium?

A

Surrounds each fascicle of muscle

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11
Q

What is the role of endomysium?

A

Envelopes each individual muscle fiber within a fascicle

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12
Q

What is a syncytium and how does it form?

A

Multinucleated muscle fiber
Formed from fusion of myoblasts during development

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13
Q

What is the function of satellite cells?

A

Skeletal muscle regeneration

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14
Q

What is a t-tubule?

A

Invagination of plasma membrane between terminal cisternae at A-I junctions

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15
Q

What is a terminal cisternae and its function?

A

Channels around sarcomere composed by SR
Reservoirs of Ca++

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16
Q

What is a triad in muscle cells?

A

T-tubule and two adjacent terminal cisternae

17
Q

What are the three types of skeletal muscle fibers?

A

Type I - slow oxidative
Type IIa - fast oxidative glycolytic
Type IIb - fast glycolytic

18
Q

What is the basic structure of cardiac muscle cells?

A

Short, cylindrical
Central, single nucleus

19
Q

How are cardiac muscle cells attached?

A

Intercalated discs

20
Q

How do organelles in cardiac muscle cells differ from skeletal muscle?

A

Large numbers of mitochondria
Smaller terminal cisternae
Diads at Z-line

21
Q

What is an intercalated disc?

A

Highly specialized cell-cell adhesion junctions

Fascia adherens
Maculae adherentes (desmosomes)
Gap junctions

22
Q

What is the basic structure of smooth muscle?

A

Bundles or sheets of small, elongated fusiform cells with tapered ends

23
Q

How does smooth muscle differ?

A

No T-system
No Z-lines
No sarcomeres
No myofibrils
Abundant gap junctions