Histology Flashcards

1
Q

Osteoprogenitor cells

A

located on bone surfaces, for example under the periosteum, these cells serve as a pool of reserve osteoblasts

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2
Q

Osteoblasts

A

bone forming cells found on the surface of developing bone. They have plentiful RER and prominent mitochondria.

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3
Q

Osteocytes

A

a bone cell trapped within the bone matrix.

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4
Q

Osteoclasts

A

large (up to 40µm or more) multinucleated cells. They are found on the surface of bone and are responsible for bone resorption.

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5
Q

Explain the histology of skeletal muscle cells?

A
  • striated
  • multinucleate (periphery)
  • unbranched
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6
Q

Explain fascicles

A
  • groups of skeletal muscle fibres

- covered by perimysin

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7
Q

What is epimysium

A
  • connective tissue that surrounds the muscle
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8
Q

What is perimysium

A
  • connective tissue around a single fascicle
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9
Q

What is Endomysium

A

-connective tissue that surrounds each muscle cell

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10
Q

Myofibrils are ___cellular

A
  • intracellular
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11
Q

What is a sarcomere?

A
  • Contractile elements of striated cells

- extended from one Z-line to another Z-Line

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12
Q

What are z-lines

A
  • Anchors actin
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13
Q

What are m-lines

A
  • Anchors myosin
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14
Q

What gives skeletal muscles it striated appearance?

A
  • myofibrils z-lines held in registry

- perpendicular to the long axis

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15
Q

What is a motor unit?

A
  • consist of one motor neurone and all the muscle fibres that it innervates
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16
Q

Describe type I muscle?

A
  • relatively slow contracting fibres

- depend on oxidative metabolism

17
Q

What colour are type I muscle cells?

A
  • Red
18
Q

What colour are type IIB muscle cells?

A
  • white

- dependant on anaerobic metabolism

19
Q

Describe histological appearance of cartilage

A
  • semi-rigid
  • permeable
  • avascular
20
Q

How does cartilage receive its nutrients?

A
  • neighbouring vessels, nutrients enter through the extracellular matrix via diffusion
21
Q

What colour does elastic cartilage appear?

A
  • yellow
22
Q

What colour is hyaline cartilage?

A
  • Blue/white
23
Q

Name given to the outer shell of dense cortical of bone?

A
  • diaphysis
24
Q

Name given to the cancellous or trabecular bone?

A
  • epiphyses
25
Q

How is bone created?

A
  • osteoblasts secrete different materials and osteoid

- this osteoid then becomes mineralised to produce bone