Drugs Flashcards
What are NSAIDs?
- Anti-inflammatory
- Analgesic
What are some examples of NSAIDs?
- Ibuprofen
- Naproxen
What are NSAIDs indicated for (rheumatology)
- inflammatory arthritis
- mechanical MSK pain
- pleuritic/pericardial pain
What are some side effects of NSAIDs?
- peptic ulcer
- dyspepsia
- oesophagitis
- renal impairment
What are DRAMDs used in (rheumatology)?
- rheumatoid arhtritis
What are some drug examples of DMARDs?
- methotrexate
- sulfasalazine
- hydroxychloroquine
DMARDs are ___slow/fast___ acting drugs?
- slow
DMARD display analgesic effect? True or false?
FALSE
What are side effects of methotrexate?
- not safe in pregnancy
What can hydroxychloroquine cause?
- retinopathy
What is a side effect of sulfasalazine in males?
- reversible oligozoospermia
What are biologics designed to target?
- different specific aspects of the immune system
What are biologics used for (rheumatology)?
- Inflammatory arthritis
- After 2 DMARDs in RA or DAS > 5.1
- After 2 NSAIDs in enclosing spondylitis
What is a side effect of biologics?
- reactivation of TB
What is an example of an Anti-TNF?
- Etanercept
- Infliximab
When are biologics indicated?
- when 2 different DMARDs have been tried with little success
What drugs are used in an acute attack of gout?
- Colchicine
- NSAIDs
- Steroids
What prophylaxis can be used for gout?
- Allopurinol (not when gout active)
- febuxostat
What are some possible side effects of corticosteroids?
- weight gain
- easy bruising
- osteoporosis
- immunosuppression
