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MSK > Drugs > Flashcards

Drugs Flashcards

1
Q

What are NSAIDs?

A
  • Anti-inflammatory

- Analgesic

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2
Q

What are some examples of NSAIDs?

A
  • Ibuprofen

- Naproxen

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3
Q

What are NSAIDs indicated for (rheumatology)

A
  • inflammatory arthritis
  • mechanical MSK pain
  • pleuritic/pericardial pain
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4
Q

What are some side effects of NSAIDs?

A
  • peptic ulcer
  • dyspepsia
  • oesophagitis
  • renal impairment
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5
Q

What are DRAMDs used in (rheumatology)?

A
  • rheumatoid arhtritis
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6
Q

What are some drug examples of DMARDs?

A
  • methotrexate
  • sulfasalazine
  • hydroxychloroquine
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7
Q

DMARDs are ___slow/fast___ acting drugs?

A
  • slow
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8
Q

DMARD display analgesic effect? True or false?

A

FALSE

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9
Q

What are side effects of methotrexate?

A
  • not safe in pregnancy
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10
Q

What can hydroxychloroquine cause?

A
  • retinopathy
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11
Q

What is a side effect of sulfasalazine in males?

A
  • reversible oligozoospermia
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12
Q

What are biologics designed to target?

A
  • different specific aspects of the immune system
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13
Q

What are biologics used for (rheumatology)?

A
  • Inflammatory arthritis
  • After 2 DMARDs in RA or DAS > 5.1
  • After 2 NSAIDs in enclosing spondylitis
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14
Q

What is a side effect of biologics?

A
  • reactivation of TB
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15
Q

What is an example of an Anti-TNF?

A
  • Etanercept

- Infliximab

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16
Q

When are biologics indicated?

A
  • when 2 different DMARDs have been tried with little success
17
Q

What drugs are used in an acute attack of gout?

A
  • Colchicine
  • NSAIDs
  • Steroids
18
Q

What prophylaxis can be used for gout?

A
  • Allopurinol (not when gout active)

- febuxostat

19
Q

What are some possible side effects of corticosteroids?

A
  • weight gain
  • easy bruising
  • osteoporosis
  • immunosuppression

MSK (16 decks)

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