Histology 2 Flashcards

1
Q

What does the epithelia do?

A

Forms barriers for protection, absorption and secretion

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2
Q

What is the epithelia?

A

Cohesive sheets of cells, with one or more layers, resting on a basement membrane.

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3
Q

Where are epithelia found?

A

‘ On the edges of us’ etc surface of our skin, lining of our mouth, lining of our gut

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4
Q

What are the 7 types of epithelium?

A

Simple squamous
Simple cuboidal
Simple columnar
Microvilli and cilia
Stratified epithelia
Pseudo-stratified epithelia
Cell junctions

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5
Q

What is simple epithelia?

A

Single layer of cells on a
basement membrane

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6
Q

What is stratified (compound) epithelia?

A

Two or more layers of cells on
a basement membrane

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7
Q

What is simple squamous epithelium?

A

Single layer of flattened plate-like cells on a basement membrane

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8
Q

Where are Simple squamous epithelium found?

A

Lines inside of blood vessels (endothelium)
Outside of lungs (mesothelium)
Abdominal organs (peritoneum)

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9
Q

What is the simple cuboidal epithelium?

A

Single layer of cells with similar height and width on a basement membrane

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10
Q

Where is simple cuboidal epithelium found?

A

Line kidney tubules
Small ducts

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11
Q

What is the simple columnar epithelium?

A

Single layer of cells taller than they are wide, on a basement membrane

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12
Q

Where is simple columnar epithelium found?

A

Line the stomach
Intestines
Uterus

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13
Q

What is microvilli?

A

Microscopic projections on luminal surface of absorptive cells

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14
Q

What is the purpose of microvilli?

A

Increase surface area
Intestinal brush border

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15
Q

What is the cilia?

A

Microscopic motile projections on luminal surface of cells

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16
Q

Where are cilia found?

A

Respiratory tract
Reproductive tract

17
Q

What are features of the stratified epithelia?

A

Protective function
Many layers of cells
Continually being worn down
Worn-away cells replaced from below

18
Q

What are the locations of stratified epithelia?

A

Found at sites subject to abrasive forces

19
Q

What is the stratified squamous non-keratinising epithelium?

A

Multiple layer of cells on a basement membrane

20
Q

Where are stratified squamous non-keratinising epithelium found?

A

Lines the mouth, oropharynx, oesophagus, vagina

21
Q

What are stratified squamous keratinising epithelium?

A

Multiple layer of cells on a basement membrane

22
Q

Where are stratified squamous keratinising epithelium?

23
Q

What is the pseudostratified epithelium?

A

Single layer of cells of variable height, mimicking multiple layers on a basement membrane

24
Q

Where are pseudostratified epithelium found?

A

Lines the conducting airways

25
What is urothelium?
Specialised stratified epithelium Breaks the rules – looks stratified, probably is stratified, but: Surface layer of umbrella cells
26
What is the basement membrane?
Composed of several extra-cellular proteins including Collagen IV and Fibronectin
27
Why is the basement membrane important?
Essential for the proper functioning and survival of the epithelium
28
With what stain can base membrane be seen?
PAS
29
What are epithelial junctions (occluding, tight junctions)?
Band-like fusions between cells that are impervious to most molecules Prevent diffusion between cells
30
What are epithelial junctions (desmosomes)?
Plaques that form physical joins between cells and connect the cytoskeletons of adjacent cells Spread forces across several cells
31
What are epithelial junctions Gap (aka communicating) junctions?
Electrical junctions that permit the transfer of small molecules Electrically couple adjacent cells
32
Which two proteins are principally involved in the generation of ciliary movement?
Tubulin and Dynein
33
A gland secretes by shedding individual cells. What type of secretion is this?
Holocrine
34
What are hemidesmosomes?
Multiprotein complex that facilitates adhesion of basal epithelial cells to underlying basement membrane