HIGH YIELD 1 Flashcards

1
Q

this is not inherited, acute onset, decreased arch height with rocker bottom appearance

A

charcot neuropathy

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2
Q

inherited, slowly progressive, weakening peripheral muscles, children/adolescents, increased arch height, hammertoe contractures

A

charcot marie tooth

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3
Q

what can cause neuropathy?

A

syphilis

leprosy

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4
Q

RF for charcot?

A

h/o
duration
s/s

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5
Q

what is a diagnostic problem of charcot?

A

resemblance to osteomyelitis

  • local inflammation
  • delayed or missed diagnosis in 25% of cases
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6
Q

volkman/virchow responsible for this german theory of charcot?

A

neurotraumatic theory

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7
Q

jean martin charcot was responsible for this french theory of charcot?

A

neurovascular theory

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8
Q

main focus of the french neurovascular theory?

A

disregulation of arterial wall smooth muscle tone leads to increased blood flow to bone because of poor vasoregulation

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9
Q

main focus of the french neurotraumatic theory?

A

multiple traumas + joint instability/overload = deterioration of joint

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10
Q

development of charcot focuses on what aspects of neuropathy?

A

sensory/motor neuropathy and autonomic neuropathy

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11
Q

main causes of charcot?

A
unknown
repetitive minor trauma
surgery
immunosuppresion 
metabolic insufficiencies
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12
Q

main cause of charcot?

A

unknown causes (74%)
trauma from repetitive stress (22-50%)
surgery (4%)

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13
Q

affect of trauma on non-DM charcot patient?

A

painful, stop WB, inflammation, decreases

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14
Q

affect of trauma on DM neuropathic patient patient?

A

nonpainful, lack of immobilization potentiates inflammatory processes

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15
Q

pro inflammatory and anti inflammatory cytokines?

A

TNFa to RANKL, IL-1B, IL-6

IL-4, IL-10

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16
Q

what does charcot require?

A

significant neuropathy

peripheral blood flow

17
Q

what are the charcot classificaiton systems?

A

eichenholz-progression
sanders and frykberg-location
brodsky-location
schon-location

18
Q

eichenholz classification stages?

A

4 of them

stage 1: development (break down)
stage 2: coalescence (repairing)
stage 3: reconstruction (ankyloses)
stage 0: prodromal (looking normal)

19
Q

Sanders and Frykberg classification?

A
1=forefoot, 3%
2=lisfrancs joint, 48%
3=choparts joint, 34%
4=STJ/AJ, 13%
5=Calcaneus, 2%
20
Q

Brodsky classification?

A

1=lisfranc/midfoot
2=STJ/TN/CC
3a=AJ
3b=Calcaneus

21
Q

Schon classification?

A

Lisfranc
Naviculocuneiform
Peri-navicular
Transverse tarsal