Herpes 2 Flashcards

1
Q

Quel est le mode de transmission du virus Epstein-barr?

A

Contact direct avec la salive (+ souvent) Kissing diseaseKissing diseaseKissing diseaseKissing diseaseKissing diseaseKissing diseaseKissing disease

Contact sexuel

Suite à l’infection primaire, réplication virale peut survenir dans épithélium oral = transmission à hôte non immun

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2
Q

Quelle maladie est associée au virus Epstein-barr?

A

Mononucléose infectieuse

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3
Q

Quelle est la séroprévalence du virus Epstein-barr chez les adultes de 30 ans?

A

95%

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4
Q

Quels sont les deux types de cancer associés au virus Ebstein-Barr?

A

Lymphome (cancer ganglions)
Carcinome nasopharyngé

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5
Q

Quels sont les manifestations cliniques du virus Ebstein-Barr?

Et les enfans?

A

Fièvre, fatigue, pharyngite, lymphadénopathie,
splénomégalie

Kids often have asymptomatic infections!!

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6
Q

Quels sont les méthodes diagnostiques du virus Ebstein-Barr?

A

Diagnostique mononucléose basé sur symptômes
Formule sanguine complète: hyperplasie et lymphocytes atypiques (monster lymphocytes)
Monotest pr recherche anticorps

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7
Q

Quelles sont les personnes à risque pour le virus Ebstein-Barr?

A

Adolescents et adultes à risque pr mononucléose infectieuse

Immunosupprimés plus à risque de maladie néoplasique mortelle

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8
Q

Where does the Epstein bar virus have as a reservoir?

A

Because it primarily infects B lymphocytes (this is why we see the monster lymphocytes) after they are killed some virus will remain in B memory lymphocytes

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9
Q

True or False,

A PCR test is recomended for patients with Mononucleosis

A

False

Reserved for Immunosupressed individuals are at higher risk

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10
Q

What type of virus is Epstein Barr?

A

it is DNA capsule since it is a herpes Veridae virus

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11
Q

At what ages is it recomended to vacinnate against EBV?

A

Aucun traitement antiviral disponible
▪ Aucun vaccin disponible

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12
Q

Décrire les traitements et les modes de prévention des infections à CMV.

A

Aucun vaccin disponible
No treatment for normal hosts (Some treatments for immunosupressed)

Because of the high risk of vertical transmission need to make sure that we educate the mothers properly: L’infection doit être évitée pendant la grossesse
Basically need to be a dedengenu: Ne pas partager les ustensiles ave ses enfant, Éviter de manger des aliments contaminés par la salive de son enfant

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13
Q

True or False,

Because of the terrible consequences of congenital disease in children that get CMV from mother, a vacination is offered to all mothers in QC

A

False,

NO VACINNE AGAINST CMV

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14
Q

Quelles sont les méthodes diagnostiques de CMV?

A

TAAN on blood or urine
Can also do serologie on normal host

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15
Q

Quelles sont les manifestations cliniques des infections à CMV chez un hôte normal?

A

Normal host no issue. It rarely causes problems in healthy people.
Some fever, fatigue but complete healing after a few days

Once CMV is in our blood we have it forever but can stay asymptomatic

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16
Q

Quelles sont les manifestations cliniques des infections à CMV chez un hôte immunosupprimé?

A

Immunosuppressed people are also at risk of a aggressive infection
Pnemonia, Encephalite, Hepatite, Nephrite
Possibly death

17
Q

Quelles sont les manifestations cliniques des infections à CMV chez un nouveau-né (infection congénitale)?

A

Congenital disease can lead to mental retardation it is the most frequent cause of congenital disease in Quebec this is why it is important for mothers to be careful

Can lead to Deafness, Splenomegalie, Microcephalie, retardation, death

18
Q

True or False,

CMV infections are usually asymptomatic and infrequent

A

False,

Very frequent: 80% of people will have it

19
Q

Quelle est l’infection congénitale la plus fréquente au Québec?

A

Cytomégalovirus (1% des bébés infectés)

20
Q

Quels sont les groupes à risque pour le CMV?

A

Bébés des mères avec séroconversion avant l’accouchement
Personnes sexuellement actives
Receveurs de transfusions de sang ou transplantation d’organes
Immunosupprimés: récurrence symptomatique