Hepatobiliary Flashcards
Acute cholecystitis needs what
Acute cholecystectomy
Within 72hrs, if delayed then after giving antibiotics
Normal bile duct calibre
4cm
Bile draining post cholesystectomy
Do ERCP and stenting or sphincterotomy if needed
What to do if bile duct got injured
Reconstruction by hepatobiliary surgeon
Pancreatic cancer with liver metastasis
Palliative chemo
Post ERCP still jaundice and new generalized abdominal pain
Do CT
To exclude ampulla trauma
Duodenal perforation
Pancreatitis
Why ERCP is technically challenging
Side view endoscope
Confirm pancreatic necrosis
FNAC for culture but it has risk of seeding infection so careful
Do before necrosectomy
Diagnostic and planning work up for gall stone
USG
Diameter of CBD
Liver function test
Difficult to dissect Calot’s triangle due to dense adhesion for exceeding timeline of 72hrs period of acute cholecystitis
Do operative cholecystoSTOMY
and leave it until situation settles
Then definitive surgery
When to do pancreatic necrosectomy
Infected necrosis on FNAC
AND hemodynamically unstable
Unable to cannulate ampulla for jaundice from carcinoma of pancreatic head
Percutaneous transhepatic cholangiogram and drain under USG
BUT before that undertake staging of the disease whether it is resectable or not cause PTC drain has high risk of dislodging
What is called when gall stone becomes impacted in Hartmann’s pouch
Mirizzi syndrome
Which makes Calot’s triangle difficult to delineate
Importance of mirizzi syndrome
High risk of CBD injury
Site of bile salts absorbtion
Ileum
Complication of mirizzi syndrome
Empyema
How to manage intra operative finding of mirizzi syndrome with empyema
Operative cholecystoSTOMY
Septic shock with RUQ tenderness without gall stone, without jaundice and normal calibre bile duct
Acute acalculous cholecystitis
Which disease is mostly associated with acalculous cholecystitis
Type 2 DM
How to scan liver lesion of HCC prior to excision
MRI
Time to appear pseudocyst after acute pancreatitis
After 4 weeks
Elevated marker of pancreatic pseudocyst
Amylase
Glasgow criteria mnemonic for both alcohol and stone related pancreatitis
PANCREAS [severe if 3 or more present]
PaO2<8kPa
Age>55yrs
Neutrophilia WCC>15k
Calcium<2mmol/L
Renal function urea>16mmol/L
Enzymes LDH>600iU/L:AST>200iU/L
Albumin<3.2g/L
Sugar>10mmol/L
Definitive Treatment of gall stone pancreatitis
Cholecystectomy once acute attack has settled
How to prevent infection in pancreatic necrosis
Imipenem
USG feature of hemangioma
Hyperechoic
Treatment of bile leak from CBD after lapcol
ERCP sphincteroTOMY and CBD stenting
This is called cystic stump leak
Which blood function do we need before ERCP
Coagulation profile
Investigation to exclude both pancreatitis and perforated viscus
Contrast CT of abdomen and pelvis
Percentage of CBD stone presenting with gall stone
10%
How to prepare coagulation profile before pancreatic cancer surgery
Vit K
LMWH
Relieve biliary obstruction with plastic stenting (metallic ones may become embedded)
How to reduce endotoxemia before pancreatic cancer surgery
Lactulose
IV mannitol
Bile salt substitution
What is endotoxemia
https://images.app.goo.gl/k8xaTqnTvtHD37Sf6
Endotoxemia is defined as the elevation of plasma levels of lipopolysaccharides (LPS) that may be due to increased gut permeability, high levels of intestinal LPS-containing bacteria, or both.
https://images.app.goo.gl/4dYMCoXma2o1ifKH9
Treatment of hepatocellular adenoma
Resection
In males it has high risk of malignant transformation
What to do if CBD stone can’t be removed even after ERCP
Choledocho duodeno stomy
Risk of Choledocho duodeno stomy
Long term risk of ascending cholangitis but are of less concern in older patients
Relation of liver function test with cholecystectomy
We can proceed with surgery if liver function is normal
Triad of cholangitis
Charcot’s triad
Pain (RUQ)
Fever (usually with rigors)
Jaundice
Rigor: a sudden feeling of cold with shivering accompanied by a rise in temperature, often with copious sweating, especially at the onset or height of a fever.
Treatment of cholangitis with CBD <4cm
ERCP & stenting