Hepatitis B Flashcards

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1
Q

“Long incubation hepatitis” = ?

A

Hepatitis B

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2
Q

What hepatitis is an endemic in many developing countries?

A

Hepatitis B

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3
Q

What are some ways in which Hepatitis B can spread?

A

Mother-fetus, sex, blood

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4
Q

What is the virus that led to the development of universal precautions from ADA and CDC for dentists in the 70s?

A

Hepatitis B

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5
Q

Is Hepatitis B an RNA or a DNA virus?

A

DNA virus

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6
Q

What virus has been found during genome sequencing of 11,000 year old human remains?

A

Hepatitis B

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7
Q

Acute symptoms of Hepatitis B are the same as Hepatitis A except it also includes:

A

Joint pain

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8
Q

Discuss the infection of Hepatitis B.

A
  • Infection can be acute or chronic
  • If acute, there is 90% resolution in adults
  • If chronic, carriers can spread infection even if no symptoms are present. There is chronic persistent hepatitis.
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9
Q

Incubation period for HBV is on average:

A

90 days (up to 3 months)

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10
Q

__% of all people worldwide will be infected with HBV at some point in their lives

A

25

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11
Q

Infection of infants and children increases the risk of chronic infection to:

A

90% and 25-50% respectively

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12
Q

What symptom is unique to HBV and not seen in HAV?

A

joint pain

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13
Q

Chronic HBV infection can lead to:

A
  • cirrhosis and liver cancer (hepatocellular carcinoma)

- also leads to chronic inflammatory responses (which ends up damaging our DNA in the liver cells)

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14
Q

How do you diagnose HBV?

A

ALT in blood (liver enzyme)

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15
Q

What determines whether you get acute or chronic HBV infection?

A

T cell response

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16
Q

Infectious particle in HBV =

A

Dane particle

17
Q

Testing for active HBV infections is usually for:

A

HbsAg

18
Q

Recombivax vaccine makes:

A

HBsAg

recomBvax = for hep B

19
Q

What vaccine can be given to pregnant women and as a post-exposure prophylaxis?

A

Recombivax (for hep B)

20
Q

50-75% of ___ is associated with HBV infection

A

HCC (hepatocellular carcinoma)