Enteric Viruses

Question 1

Most enteric viruses are naked, EXCEPT:

Answer 1

coronaviruses! These are enveloped and enteric

Question 2

Naked virus that mainly infects the young; causes diarrheal diseases.

Answer 2

Rotavirus

Question 3

Like flu, rotaviruses infect what cells?

Answer 3

columnar epithelial cells

Question 4

Rotavirus is a __RNA virus.

Answer 4

dsRNA virus

Question 5

Why doesn’t the dsRNA virus (rotavirus) induce a strong IFN response, like with the flu virus?

Answer 5

Because it has three capsid layers! Which keeps it protected and hidden.

Question 6

What does the rotavirus do to avoid IFN response?

Answer 6

It does transcription within itself, and then squirts out the ssRNA to the cytoplasm. During assembly is when the dsRNA forms. So it stays hidden a lot of the time so that the immune system doesn’t detect it quickly.

Question 7

Most of the time, polio is ___

Answer 7

asymptomatic

Question 8

EV-D68 and EV-A71 is associated with:

Answer 8

Acute Flaccid Myelitis (AFM)
know there is a link between EV-D68 and AFM
(acute FLACCID –> “dick” “69”)