Hepatitis A

Question 1

Rules regarding blood borne pathogens are established by:

Answer 1

OSHA

Question 2

Inflammation of the liver:

Answer 2

hepatitis

Question 3

What are the 7 things associated with acute hepatitis?

Answer 3

1) Fatigue
2) Abdominal pain
3) Loss of appetite
4) Nausea
5) Vomiting
6) Darkening of urine
7) Jaundice

Question 4

What causes jaundice?

Answer 4

buildup of bilirubin in the blood

Question 5

Bilirubin is a biproduct of:

Answer 5

hemoglobin metabolism

Question 6

Chronic hepatitis can lead to:

Answer 6

fibrosis –> cirrhosis

Question 7

“infectious hepatitis” = ?

Answer 7

Hepatitis A

Question 8

“serum hepatitis” = ?

Answer 8

Hepatitis B

Question 9

Alcohol abuse, some drugs (like ___), and toxic chemicals (like __ __) can also cause or worsen hepatitis.

Answer 9

• acetaminophen

- organic solvents

Question 10

What types of viral hepatitis are RNA viruses?

Answer 10

Hepatitis A and C

Question 11

What type of capsid does Hepatitis A have?

Answer 11

Icos

Question 12

Does Hepatitis A have an envelope?

Answer 12

No - it is a naked virus

Question 13

What family is Hepatitis A in?

Answer 13

Picorna-

Question 14

Since most recent outbreaks of Hepatitis A, there have been ___ cases.

Answer 14

25,000

Question 15

What type of viral hepatitis is mostly transmitted fecal-orally?

Answer 15

Hepatitis A

Question 16

Hepatitis A can be transmitted through contaminated food, such as:

Answer 16

vegetables and shellfish

Question 17

“short incubation hepatitis” = ?

Answer 17

Hepatitis A

Question 18

“long incubation hepatitis” = ?

Answer 18

Hepatitis B

Question 19

Hepatitis A causes __ infection only.

Answer 19

acute

Question 20

Chronic carrier states are seen with what viral hepatitis?

Answer 20

Hepatitis B or C

Question 21

Symptoms for Hepatitis A typically last:

Answer 21

8 weeks

Question 22

What is the incubation period for Hepatitis A?

Answer 22

15-45 days (about 1 month)

Question 23

Viral hepatitis that is a typical enterovirus in most ways; it is very hard to decontaminate due to it being resistant to heat and disinfectants.

Answer 23

Hepatitis A

Question 24

Hepatitis A has an __RNA genome

Answer 24

+ssRNA genome

Question 25

Hepatitis A is mostly released from cells by:

Answer 25

exocytosis

Question 26

The Hepatitis A pathogenesis is the result of:

Answer 26

T cell immune response in the liver, not by the virus itself; the body causes the pathogenesis!

Question 27

What are the ways to test for Hepatitis A?

Answer 27

1) Antibodies present in body against Hepatitis A

2) High liver enzymes (aminotransferases)

Question 28

What are the three main prevention and treatment options for Hepatitis A?

Answer 28

Hygiene, vaccines, and immune serum

Question 29

Discuss the vaccine for Hepatitis A.

Answer 29

• Inactivated
• 100% effective
• Recommended for travelers
• Once you get the vaccine, you have life-long immunity

Question 30

How does one get life-long immunity to Hepatitis A?

Answer 30

Vaccine or Hepatitis A infection

Question 31

Under what circumstance is the immune serum given for Hepatitis A?

Answer 31

Immune serum has antibodies that can be given to travelers PRE-exposure if they’re leaving for travel too soon for the actual vaccine to work

Immune serum can also be given POST-exposure as prevention for worsening of symptoms

Question 32

Vaccines for Hepatitis A can be administered up to __ post exposure.

Answer 32

2 weeks

Question 33

HAV vaccine is an:

Answer 33

inactivated virus vaccine