Henoch-Schonlein purpura - week 17

Question 1

what is Henoch–Schönlein purpura?

Answer 1

small vessel vasculitis
blood vessels in skin, joints, intestines and kidneys become inflamed and bleed

Question 2

Epidemiology of Henoch–Schönlein purpura?

Answer 2

usually in children and adolescents

Question 3

pathology of Henoch–Schönlein purpura?

Answer 3

IgA vasculitis
IgA deposits in the blood vessels

Question 4

presentation of Henoch–Schönlein purpura?

Answer 4

The four classic features:
purpura - rash on legs and buttocks (100%),
joint pain (75%),
abdominal pain (50%)
renal involvement (50%).

GI bleeding
arthralgia

Question 5

investigations into Henoch–Schönlein purpura?

Answer 5

biopsy of affected tissue shows a vasculitis with IgA deposits in the vessel wall