Hemodynamics Part II: infarct

Question 1

define infarction

Answer 1

death of tissue (ischemic necrosis) due to interruption in blood supply

Question 2

what are some causes of infarction besides thrombosis and emboli?

Answer 2

vasospasm
hemorrhage within atherosclerotic plaque
extrinsic compression of vessel
twisting of vessel (testicular torison, intestinal volvulus)

Question 3

infarct is much more likely in organs with ______

Answer 3

single venous outflow

Question 4

what is the shape of typical infarcts?

Answer 4

wedge shaped

over time the infarct is delineated by a rim of hyperemia reflecting inflammation oat the edge of the lesion

Question 5

where does a “red” hemorrhagic infarct usually occur

Answer 5

venous occlusions
loose tissues
tissues with dual circulation (lung, bowel)

Question 6

where does a “white” anemic infarct usually occur?

Answer 6

typical of arterial occlusions in solid organs with limitation of blood flow into areas of ischemic necrosis

Question 7

the origin of an embolus is infected tissue

Answer 7

septic infarct

major source: bacterial endocarditis

Question 8

what can septic infarcts progress to?

Answer 8

abscess