Hematopoiesis

Question 1

Name 3 of the 4 characteristics of stem cells.

Answer 1

• may proliferate extremely well
• self-renewing
• may differentiate into several (at least 2) different cell types
• may reconstitute tisues after injury

Question 2

Totipotent cells

Answer 2

Totipotent cells give rise to ALL cells of an organism, including embryonic and extaembryonic tissues (cells which support embryonic development).

• A zygote is totipotent

Question 3

Pluripotent cells

Answer 3

Pluripotent cells give rise to all cells of the embryo and subsequently adult tissues. (Embryonic stem cells)

Question 4

Mulitpotent cells

Answer 4

Multipotent cells give rise to different cell types of a given lineage (adult stem cells)

Question 5

Which cells could also be called embryonic stem cells?

Answer 5

Pluripotent cells

Question 6

Which cells could also be called adult stem cells?

Answer 6

Multipotent cells

Question 7

Name 3 of the 4 characteristics of embryonic stem cells.

Answer 7

1. dervied from the inner-dell mass of a blastocyst
2. pluripotent, differentiate to all cell lineages
3. technical and ethical limitation
4. may be induced from adult tissues

Question 8

Name 2 of the 3 characteristics of adult stem cells.

Answer 8

1. Harvested from mature organs/ tissues (bone marrow)
2. multipotent
3. more restricted ability to produce different cell tpes and to self-renew

Question 9

what are some characteristic of hematopoiesis during 2-8 weeks of gestation?

Answer 9

• blood islands are found in the yolk sac wall
• nucleated erythrocytes are present
• no leukocytes

Question 10

What are some characteristic of hematopoiesis during