hematopoiesis Flashcards
0
Q
PPSC gives rise to what 2 cells?
A
CFU-GEMM
CFU-L
1
Q
what is the one cell all blood cells are derived from?
A
pluripotential stem cell
PPSC
2
Q
CFU-GEMM gives rise to what cells?
A
CFU-E (rbc's) CFU-GM (pmn's and monocytes) CFU-Eo (eos) CFU-Ba CFU-Meg (platelets)
3
Q
what factors need to be present for a RBC to develop from CFU-GEMM?
A
erythropoietin
GM-CSF
IL-3 and IL4
4
Q
what factors need to be present for a neutrophil to develop from CFU-GEMM?
A
GM-CSF
G-CSF
IL-3
5
Q
what factors need to be present for a basophil to develop from CFU-GEMM?
A
IL-3
GM-CSF
6
Q
what factors need to be present for an eosinophil to develop from CFU-GEMM?
A
GM-CSF
IL-3
IL-5
7
Q
what factors are needed for a monocyte to develop from CFU-GEMM?
A
GM-CSF
IL-3
M-CSF
8
Q
what is needed for a platelet to develop from CFU-GEMM?
A
thrombopoietin
GM-CSF
IL-3
