Blood Flashcards
what is the most abundant plasma protein?
albumin
what is a hematocrit
volume of packed RBCs
what is the difference between serum and plasma?
serum has clotted
plasma has NOT clotted (still has clotting factors)
what protein maintains the shape of RBCs?
spectrin
what organelles do reticulocytes have?
mitochondria, golgi, and ribosomes
what are the 3 main types of granules in cytoplasm of PMNs?
specific, azurophilic, tertiary (phosphasomes + metalloproteinases)
specific granules have what properties?
pink
antibacterial
azurophilic granules have what properties?
purple
lysosomes
tertiary granules contain what properties?
help the neutrophil move through the ECM
what do neutrophils release that causes a fever?
IL-1
what is diapedesis?
how PMNs leave the venules and pass b/w endothelial cells and penetrate connective tissue
what 2 major granules are in eosinophils?
specific granules and azurophilic
what 4 major proteins are in their specific granules?
major basic protein
eosinophil cationic protein
eosinophil peroxidase
eosinophil-derived neurotoxin
what hydrolytic enzymes are in eosinophils?
histaminase and arylsulfatase (neutralize histamine and leukotrienes)
what granules are in basophils?
basophilic specific granules
what are in the basophilic specific granules?
histamine, heparin, heparin sulfate, and leukotrienes
what 2 types of granules do platelets have (but you can’t see)
alpha and dense
what are in alpha granules in platelets?
adhesion molecules
platelet derived growth factor
fibrinogen
what are in dense granules in platelets?
calcium
ADP
ATP
serotonin
