Blood Flashcards

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0
Q

what is the most abundant plasma protein?

A

albumin

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1
Q

what is a hematocrit

A

volume of packed RBCs

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2
Q

what is the difference between serum and plasma?

A

serum has clotted

plasma has NOT clotted (still has clotting factors)

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3
Q

what protein maintains the shape of RBCs?

A

spectrin

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4
Q

what organelles do reticulocytes have?

A

mitochondria, golgi, and ribosomes

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5
Q

what are the 3 main types of granules in cytoplasm of PMNs?

A

specific, azurophilic, tertiary (phosphasomes + metalloproteinases)

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6
Q

specific granules have what properties?

A

pink

antibacterial

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7
Q

azurophilic granules have what properties?

A

purple

lysosomes

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8
Q

tertiary granules contain what properties?

A

help the neutrophil move through the ECM

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9
Q

what do neutrophils release that causes a fever?

A

IL-1

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10
Q

what is diapedesis?

A

how PMNs leave the venules and pass b/w endothelial cells and penetrate connective tissue

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11
Q

what 2 major granules are in eosinophils?

A

specific granules and azurophilic

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12
Q

what 4 major proteins are in their specific granules?

A

major basic protein
eosinophil cationic protein
eosinophil peroxidase
eosinophil-derived neurotoxin

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13
Q

what hydrolytic enzymes are in eosinophils?

A

histaminase and arylsulfatase (neutralize histamine and leukotrienes)

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14
Q

what granules are in basophils?

A

basophilic specific granules

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15
Q

what are in the basophilic specific granules?

A

histamine, heparin, heparin sulfate, and leukotrienes

16
Q

what 2 types of granules do platelets have (but you can’t see)

A

alpha and dense

17
Q

what are in alpha granules in platelets?

A

adhesion molecules
platelet derived growth factor
fibrinogen

18
Q

what are in dense granules in platelets?

A

calcium
ADP
ATP
serotonin