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Cell Bio Block 2 > cartilage > Flashcards

cartilage Flashcards

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0
Q

what are the 3 kinds of cartilage?

A

hyaline cartilage
elastic cartilage
fibrocartilage

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1
Q

what are the cells in cartilage?

A

chondrocytes

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2
Q

what is perichondrium and where is it found?

A

dense connective tissue covering that is NOT on:
articular cartilage
epiphyseal plates
fibrocartilage

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3
Q

what are isogenous groups?

A

cells that have recently divided

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4
Q

what are 2 important functions of hyaline cartilage?

A

model for developing skeleton of fetus

makes up epiphyseal plate/growth plate that serves to elongate bones

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5
Q

what makes up the bulk of the fibrils of collagen in hyaline cartilage matrix?

A

type 2 collagen

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6
Q

which type of collagen facilitates fibril interaction with the matrix proteoglycans?

A

type 9

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7
Q

which type of collagen organizes collagen fibrils into hexagonal lattice?

A

type 10

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8
Q

which type of collagen regulates fibril size?

A

type 11

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9
Q

which type of collagen is found near the periphery of chondrocytes?

A

type 6

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10
Q

what do GAG’s do?

A

join to the protein core to form a proteoglycan monomer

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11
Q

what are the 3 kinds of GAGs?

A

hyaluronan
chondroitin sulfate
keratan sulfate

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12
Q

what is the most important proteoglycan monomer?

A

aggrecan (high affinity for water)

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13
Q

what are multiadhesive glycoproteins?

A

non-proteoglycan linked glycoproteins that influence interactions b/w chondrocytes and matrix molecules

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14
Q

which multiadhesive glycoproteins have clinical value as markers of cartilage turnover and degeneration?

A

anchorin CII: collagen receptor on chondrocytes

tenascin and fibronectin: anchor chondrocytes to the matrix

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15
Q

what does articular cartilage do?

A

protects the ends of long bones and helps lubricate synovial joints

16
Q

what are 2 key features of articular cartilage?

A

poor healing because of avascularity

NO perichondrium

17
Q

what is elastic cartilage?

A

has components of hyaline cartilage and matrix along w/ elastic fiber sand sheets of elastic material
DOES HAVE A PERICONDRIUM

18
Q

what does elastic cartilage stain with?

A 
orcein= elastic fibers + cells
resorcin= elastic fibers only
19
Q

what is fibrocartilage?

A

combo of hyaline cartilage and dense regular connective tissue

20
Q

what is a distinguishing feature of fibrocartilage?

A

rows= ‘trains’ of chondrocytes

DOES NOT HAVE A PERICHONDRIUM

Cell Bio Block 2 (10 decks)

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