Adipose Tissue Flashcards
What plays a part in adipocyte differentiation?
peroxisome proliferator-activated receptor gamma (PPARgamma)
what cells are adipose tissue composed of?
adipocytes
what are the characteristics of white adipose tissue?
in adults
unilocular (1 fat droplet)
nucleus and cytoplasm is displaced to the edges by the fat droplet
large
what are the characteristics of brown adipose tissue?
mostly in fetuses
multilocular (numerous fat droplets)
central nucleus
LOTS of MITOCHONDRIA
where is brown adipose tissue in adults?
around kidneys adrenal glands aorta regions of neck mediastinum
what is the process called when brown fat generates heat?
non-shivering thermogenesis
what regulates non-shivering thermogenesis in humans?
UPC-1 or thermogenin in the mitochondria
what is a lipoma
benign adipose tissue tumor
what is a liposarcoma?
rare, malignant tumor w/ cells that are less differentiated
what is a hibernoma?
rare, benign, slow-growing tumor of brown fat
usually a mix of white and brown unless it is a pure hibernoma