Hematolopoegic Function Flashcards
Function of RBC
Transport O2 to tissues and CO2
Participates in acid base balance
Eyrhoropoiesis
RBC production
Anemia
Low level RBC from blood loss, hemolysis (destruction), deficient RBC production due to lack of nutrients/bone marrow failure
Effects of anemia
Pallor skin
Conjunctival
Tachycardia
Palpitations
Hemolytic anemia
Premature destruction of RBC
Retention of iron
Fatigue , despnea
Ex: sickle cell
red blood cells are destroyed faster than they can be made.
Iron deficiency anemia
Results from dietary deficiency Fatigue Dyspnea tachycardia Pallor Brittle hair
Megoblastiic anemia cause
Vitamin B12 deficiency and folic acid deficiency
Aplastic anemia
Disorder of pluripotent I bone marrow results in reduced RBC, WBC, PLT
Sudden onset
A rare condition in which the body stops producing enough new blood cells.
Aplastic anemia develops as a result of bone marrow damage. The damage may be present at birth
Causes of aplastic anemia
Exposure to high doses of radiation, chemicals, chemo, aids
Treatment to aplastic anemia
Stem cell replacement and RBC transfusions
Polycythemia
High RBC- Hematocrit >50%
Absolute polycythemia
Primary: increased RBC WBC PLT
splenomegaly, hypertension, dizziness, itching, and pain
Treatment of primary polycythemia
Phlebotomy, ASA
Secondary polycythemia
Physiological increase in erythropoietin usually as a compensatory response