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USMLE Step 3 > Hematology > Flashcards

Hematology Flashcards

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USMLE® Step 1 flashcards
1
Q

<p>CLL treatment for stage 2,3,4 leukemia</p>

A

<p>Fludarabine combinend with rituximab(most likely to extend survival)</p>

-Alentuzumab and ibrutinib for fludarabine failures.

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2
Q

<p>Hairy cell leukemia treatment</p>

A

<p>Cladribine (2-CDA)</p>

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3
Q

<p>most common cause of death in myeloma multiple</p>

A

<p>Infection and renal failure</p>

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4
Q

<p>Prognosis indicator for Multiple myelomas</p>

A

<p>Beta 2 microglobulin level</p>

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5
Q

<p>aplastic anemia treatment</p>

A

<p><50: bone marrow transplant

| >50:anti-thymocyte globulin and cyclosporine</p>

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6
Q

<p>lymphoma treatment</p>

A

<p>Stage I and II: Radiation and chemo
Stage III and IV: Chemo
HL:ABVD (adriamycin, bleomycin, vinblastine and dacarbazine)
NHL:CHOP + rituximab( if CD20+)
cyclophosphamide,hydroxyadriamycin,oncovin,prednisone.</p>

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7
Q

<p>ITP treatment

| </p>

A

<p><20,000= IVIG

| >20,000=prednisone</p>

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8
Q

<p>Exchange transfusion indication in neonatal hyperbili</p>

A

<p>>20 or kernicterus </p>

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9
Q

<p>osteomyelitis treatment in G6PD deficiency</p>

A

<p>Ceftria + Clinda or vanco</p>

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10
Q

<p>neonatal polycythenmia</p>

A

<p>>65%</p>

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11
Q

<p>Causes of aplastic anema

| Can Make New Blood Cells Properly</p>

A 
<p>Carbamazepine
Metimazol
NSAIDs
Benzeno
Cloranfenicol
Propilthiuracilo
</p>
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12
Q

<p>diference between Iron deficiency anemia and chornic diesease anemia</p>

A

<p>Iron def: Elevated RDW

| CDA:low TIBC and High ferritin</p>

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13
Q

<p>-Iron studies in thalasemia</p>

A

<p>Normal

| </p>

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14
Q

<p>best inial study for anema</p>

A

<p>CBC with peripheral blood smear</p>

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15
Q

<p>first step in patient with sickle cell disease and fever</p>

A

<p> GIVE ANTIBIOTICS STAT!!!!

| -Ceftrixone,levoflox or moxi</p>

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16
Q

<p>indications for exchange transfusion in sickle cell anemia</p>

A

<p>-Stroke

- Retinal infraction
- Pulmonary infection
- Priapism</p>

17
Q

<p>most accurate test for Autoimmune hemolysis</p>

A

<p>-Coombs test</p>

18
Q

<p>Cold agglutinins hemolysis</p>

A 
<p>Mycoplasma or EBV
Coombs NEGATIVE
</p>
complement test is positive
GIVE RITUXIMAB
19
Q

best initial test for G6PD def.

A

HEiz body test, bite cells.

20
Q

Hereditary spherocytosis findings

A

Galllstones

elevated MCHC

21
Q

most accurate test for Hereditary spherocytopsis

A

eosin-5meleimide

22
Q

Initial treatment for AML

A

Idarubicin(or daunorubicin) and arabinoside.

Plus ATRA if M3

23
Q

high hematocrit, low MCV with LOW erythropoietin level

A

Pvera

24
Q

best inial test for lymphoma

A

Excisional lymph node biopsy

25
Q

best initial test for VWD

A

Ristocetin cofactor assay

Von willebrands factor

26
Q

VWD treatmetn

A

1-.Desmopression
2-.DDAVP
3-.Factor VIII
4-.Reconvinant VWF

27
Q

Hemophilia best initial test

A

Mixing study, then specifica factor lever

28
Q

treatmetn for Warfarin overdose

A

PCC(Prothrombin complex concentrate)

29
Q

45 yo patient with GERD SYMPTOMS

A

SCOPE

30
Q

Treatment for AML

A

Idarubicin(or daunorubicin) + cystosine arabinoside + ATRA(in m3)

31
Q

treatment for CML

A
  • imatinib

- Dasatinib and nilotinib for non responders

32
Q

treamtnet for policithemia vera

A
  • Phlebotomy
  • hydroxyurea
  • Ruxolitinib is uses when hydroxiurea fails.
33
Q

most common type of Hodkin lymphoma

A

Nodular sclerosing type

34
Q

autoinmmune anemia treatmetn( IgG)

A

STEROIDS

35
Q

hereditary spherocytosis

A

elevated MCHC>36

36
Q

AML treatment

A

idarubicin(or daunorubicin) + ATRA

37
Q

CLL

A
  • Fludarabine + rituximab
  • añemtuzumab and ibrutinib for failures

treat only if anemia,trombocypenia or splenomegaly

38
Q

CML treatmetrn

A

Imatinib

39
Q

Essentia trombocytopenia treatment

A

Hydroxyurea (firts line)

Anagrelide

USMLE Step 3 (19 decks)

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