Hematologic System Disorders and Treatments - Platelet Disorders and Treatment (Hemophilia & Thrombocytopenia) Flashcards
Hemophilia
A genetically inherited disease that’s generally characterized by a deficiency of certain clotting factors (factor VII and factor IX), which prevents the blood from clotting
Which two clotting factors essential components of the coagulation pathway?
- Factor VII
* Factor IX
Deficiencies of any of these clotting factors prevent ____
Blood from clotting, resulting in bleeding episodes
Hemophilia is treated by ____
Infusing factors that are available as injectable medications
Hemophilic patients may lose a lot of blood, which means many patients require ____
Frequent blood transfusions
Thrombocytopenia
An abnormally low level of platelets in the blood
Thrombocytopenia is a general condition that stems from an ____
Underlying disease
Low levels of platelets can be due to what four things?
- Chronic liver disease, causing the spleen to enlarge and destroy platelets
- Antibodies to platelets in some individuals
- Diseases of the bone marrow, resulting in inadequate production of platelets
- Certain medications (such as Heparin)
Because platelets are involved in the initial steps of blood clotting, thrombocytopenia creates a risk for ____
Prolonged bleeding
Treatment of Thrombocytopenia involves ____ or ____
- Treating the underlying disease
* discontinuing offending medications