Hematologic System Disorders and Treatments - Macrocytic Anemia & Anemia of Chronic Diseases

Question 1

Macrocytic Anemia

Answer 1

When the body forms very large RBCs

Question 2

The main cause of macrocytic anemia is a ____ and ____ deficiency

Answer 2

• Vitamin B12

* Folic acid

Question 3

Common medications for treatment of macrocytic anemia are:

Answer 3

• Vitamin B12 supplementation

* Folic Acid supplementation

Question 4

Most B12 in a diet comes from ____

Answer 4

Animal products

Question 5

Folic acid is found in ____, ____, and ____

Answer 5

• Fresh green vegetables
• Meat
• Eggs

Question 6

Severe deficiency may require a ____

Answer 6

Prescription

Question 7

____, ____, or ____ can also lead to folic acid deficiency

Answer 7

• Alcoholism
• Liver disease
• Renal failure

Question 8

Anemia can be caused by certain chronic diseases, such as ____ or ____ disease, ____, and ____

Answer 8

• Renal disease
• Kidney disease
• Cancer
• HIV

Question 9

Kidney or renal disease can result in decreased production of ____, leading to anemia

Answer 9

Erythropoietin

Question 10

Erythropoietin

Answer 10

A hormone produced in the kidneys that stimulates RBC production

Question 11

Common medications for the treatment of anemia due to chronic diseases are:

Answer 11

• Epoetin alpha (Epogen, Procrit)

* Darbepoetin alpha (Aranesp)

Question 12

The most common side effects of these medications are ____ and ____. Patients at increased risk of thrombosis due to other factors need to be watched closely for these side effects. For some patients, risks will need to be evaluated against benefits.

Answer 12

• Hypertension

* Thrombosis