Heart Valve Disease Flashcards
Define valvular heart disease
Damage to or a defect in one or more of the four heart valves
What are the four valves in the heart?
Mitral - LA to LV
Aortic - LV to Aorta
Tricuspid - RA to RV
Pulmonary - RV to Pulmonary aa
What are the main causes of valvular heart disease?
Congenital Rheumatic Degenerative Cardiac remodelling Infective endocarditis
Describe congenital VHD
VHD caused by a congenital defect
-bicuspid aortic valve causes aortic stenosis
Describe rheumatic VHD
Damage to connective tissue of heart valves caused by rheumatic fever
-mitral/tricuspid/aortic stenosis
Describe degenerative VHD
Progressive process of slow degeneration
-mitral/tricuspid
Describe cardiac remodelling VHD
Cardiac remodelling can lead to VHD
- hypertrophy/dilatation leading to regurg
- raised pressure causing stenosis
Describe how infective endocarditis can cause VHD
Heart valves not directly supplied with blood, hard to fight infection
-aortic regurgitation
Describe the difference between stenotic and regurgitation valvular disease
Stenosis - narrowing of a valve opening causing lowered blood flow
Regurgitation - blood flows back through valve after leaflets close
What are the main causes of mitral stenosis?
Rheumatic heart disease
What are the main sx/signs of mitral stenosis?
Sx - Dysnpoea, haemoptyis, palpitations (AF), RHF
Signs - Malar flush, JVP, left parasternal heave
Describe the murmur of mitral stenosis
Low pitched mid-diastolic murmur
-heard loudest at apex
What are the main causes of mitral regurgitation?
Endocarditis
Papillary muscle rupture post MI
LV dilation (LVF, HOCM)
Mitral prolapse
What are the main sx/signs of mitral regurgitation?
Sx - Palpitations (AF), dyspnoea/orthopnoea, RHF/CCF
Signs - Displaced apex beat, systolic thrill
What are the main causes of aortic stenosis?
Calcification of aortic valve
Rheumatic fever
Congenital bicuspid (most common)