Hair Flashcards
In utero, babies molt body and scalp hair when?
22 and 28 weeks
Hair in the Anagen phase does not come out, it is rooted very deeply. How long does this growth phase last?
1-5 years
Hair in the Telogen phase does come out, its root is closer to the surface. This phase lasts
3 months
What is androgentic alopecia
Common ass baldness
What is the mechanism of androgentic alopecia
Gradual minituriazation of the hair. Transformation of large terminal follicles to small vellus follicles. The hair becomes basically invisible. SO with common baldness, you’re not actually losing hair as much as the follicles and hair are just becoming tiny.
Male pattern androgentic allopecia
frontotemporal recession and vertex thinning, loss of all scalp hair exceptociptial fringe
Femal pattern baldness
women tend to just lose the hair from their crowns
female pattern baldness usually starts when?
25-35
Lab tests for male pattern androgentic allopecia appearing in women
DHEAS and testosterone levels
The inheritance pattern for androgentic allopecia is…
autosomal dominant or multifactorial. can come from anywhere.
What is the moa of minoxidil?
Increases hair density either by induction of anagen stage or decrease in anagen stage duration. hair diameter is increased.
No one is completely sure how it works
Doctor in miami,,,,bedside observation that led to treatment
2% minoxidil for
women
5% for
men
WHAT HORMONE CAUSES MALE PATTERN LOSS IN GENETICALLY SUSCEPTOBLE INDIVIDUALS
5 ALPHA DIHYDROTESTOSTERONE….KNOW THIS
HOW DOES FINESTERIDE WORK?
IT INHIBITS 5 ALPHA REDUCTASE WHICH MAKES 5 ALPHA DIHYDROTESTOSTERONE