Anti-virals Flashcards

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1
Q

All of the -cyclovirs do what?

A

Competitively inhibit DNA polymerase, compete with deoxygunosine triphosphatefor entry into viral DNA

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2
Q

Acyclovir used to treat

A

VZV

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3
Q

Acyclocir

A

seizures. acyclovir makes you psycho

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4
Q

Famciclovir

A

VZV and HHV-8 (latent)valacyclovir

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5
Q

AE of famciclovir

A

Can cuase nephrotoxicity.

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6
Q

Ganciclovir treats

A

HHV 6 and 8 (active)

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7
Q

AE of Ganciclovir

A

Teratogenic and myelosuppresive

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8
Q

valacyclovir

A

pro-drug, treats VZV and HHV-8 Latent

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9
Q

Valgancyclovir

A

HHV6 and 8 latent. myelosuppresive and t4eratogenic

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10
Q

CIDFOVIR

A

this is a non-cyclovir and the non-cyclovirs are not reliant on intracellular kinase phosphorylation as a prerequisite for activity so they…ARE ACTIVE AGINST KINASE deficient strains

Pox family and hhv 6,7,8

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11
Q

foscarnet

A

hhv 6

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