Haematology III Flashcards
How do red blood cells differ from white blood cells?
WBC are nucleated in contrast to RBC
What are whiteblood cells also known as? e.g RBC = Erythrocytes
LEUKOCYTES
WBC fucntion?
- defense vs pathogens
- toxin and waste removal
- remove damaged cells
What are the 4 main characteristics of WBC?
- Phagocytosis
- Amoeboid movement
- attracted towards specific chemical stimuli
- EXTRAVASATION (migrates out of blood stream)
What is amoeboid movement?
- is how white blood cell move by cytoplasmic projection(crawling like movement)
Which WBC are phagocytes?
Neutrophils, Eosinophils, Monocytes
What are the 5 WBC in the body?
Neutrophils
Lympocytes
Monocytes
Eosonophils
Basophils
(never let monkey eat banana)
What is the healthy Wbc count?
4-11 x 10^9 (per L of blood)
What is the healthy Wbc count?
4-11 x 10^9 (per L of blood)
In what two categories do WBC subdivide in?
- Granulocytes
- Agranulocytes
Which WBC are granulocytes?
Neutrophils
Basophils
Eosinophils
Which WBC are Agranulocytes?
Lymphocytes
Monocytes
What is the RBC : Platelets : WBC ratio?
700 : 40 : 1
What is the percentage composition of each type of WBC?
N = 50-70%
L = 20-30%
M = 2-10 %
E = 2-4 %
B = <1%
What is the lobe structure of WBC? (Structure)
- N = 2-5 lobes
- L = Single round nucleus
- M = Horshoe shaped nucleus
- E = bilobed/ 2 lobes
- B = Bilobed S-shaped
What is the smallest and largest WBC?
Monocytes Largest
Lymphocytes Smallest
Function of neutrophils?
- first line of defence against bacterial infection
- (P)hagocytotic
- (M)obile
- 10 hours
- (major constituent of pus)
Function of EUSONOPHILS?
- (T)oxins
- (A)llergies/Asthma
- (C)ombat parasites/bacteria
- 8 to 12
Function of EUSONOPHILS?
- Release toxic compounds
- Allergies/Asthma
- Combat parasites/bacteria
- 8 to 12
Basophils function?
- Inflammatory response
Monocytes function?
- Phagocytic
- Migrate out of cell becoming macrophage
Lymphocytes function?
Central role in all immunological defence mechanisms
What type of lymphocytes?
T-cell
B-cells
NK cells (prevent CANCER)