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BODY SYSTEMS > Haematology I > Flashcards

Haematology I Flashcards

1
Q

What is the difference between plasma fluid and blood?

A

Blood is the main circulating fluid in the body
- PLASMA fluid is part of the blood that contain nutrients such as water, glucose, amino acids, proteins, hormones, vitamins, minerals, antibodies, and dissolved carbon dioxide.

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2
Q

What is the volume of BLOOD in the average adult?

A

5L

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3
Q

What type of tissue is blood?

A

Specialised connective tissue

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4
Q

What is BLOOD composed of?(4)

A
  • Plasma
  • RBC
  • WBC
  • Platelets
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5
Q

What is the percentage composition of each component of the blood?

A
  • Plasma = 55%
  • WBC and PLATELETS = <1%
  • Red blood cells= 45%
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6
Q

What is each components of the plasma fluid composition?

A
  • 92% water
  • 7% protein
  • 1% other solutes
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7
Q

What is ERYTHROPOIESIS?

A

Red blood cell formation

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8
Q

What is HAEMOPOIESIS?

A

its how blood cells are (just general)

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9
Q

What is Thrombocytes formed for?

A

Megakaryocytes

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10
Q

What does myoBLAST subdivide into?

A
  • Basophils
  • neutrophils
  • eusonophils
  • monocyte = Macrophages
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11
Q

Describe the formation of RBC in terms of HAEMATOPOIESIS?

A

1) Multipotent hemopoietic stem cell
2) Common MYELOID progenitor
3) Erythrocytes
4) RBC

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12
Q

What can the common MYELOID progenitor differentiate into?(4)

A

Megakaryocyte
Erythrocyte
Mast cell
MyoBLAST

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13
Q

Describe the the formation of plasm B cell in terms of HAEMTOPOIESIS process?

A
  • Multipotent HEAMPOIETIC stem cell
  • common LYMPHOID progenitor
  • B cells
  • Plasm B cells
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14
Q

Describe erythropoiesis?

A
  • Hecmocytoblast/Multipotent Hemaoietic stem cell
  • ProerythroBLAST
  • EARLY eryhtroBLAST
  • Late erythroBLAST
  • NomoBLAST
  • Reticucolocyte
  • ERYthrocytes
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15
Q

What are the 3 phases that occur during the developmental cell?

A
  • Ribosome synthesis
  • Haemoglobin accumulation
  • Ejection of nucleus
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16
Q

What is eryhtroPOIETIN?

A

growth factor, acts on precursor converting it to RBC

17
Q

What are all the elements require for HAEMOGLOBIN (RBC)development?

A
  • Iron
  • Vitamin B12 & Folic acid
  • intrinsic factor
  • Amino acids
18
Q

Where does eryhtoropoieSis occur in foetus?

A

early in yolk sac, then in liver & spleen and then in bone marrow at end of the pregnancy

19
Q

Where does eryhtorpoieSis occur in infants/little kids?

A

Bone marrow

20
Q

Where does erythropoieSis occur in Adults?

A

RED bone marrow only!

21
Q

What is the lifespan of a RBC?

A

120 days

22
Q

What happens when a red blood cells comes at the end of its life span?

A

it is Recycled

BODY SYSTEMS (22 decks)

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