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JazRespiratory > Haematology > Flashcards

Haematology Flashcards

1
Q

IDA causes ____ anaemia

A

microcytic (so does chronic little blood loss

small RBCs

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2
Q

Stored iron is measured by serum ____

A

ferritin

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3
Q

macrocytic anaemia causes=

A

vitamin B12 or folate deficiency - MCV increased

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4
Q

normocytic anaemia causes=

A

acute blood loss, chronic inlammation/infection

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5
Q

causes of macrocytic RBCs w/o anaemia

A

alcoholism, liver disease, hypothyroidism

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6
Q

Causes of a raised Hb concentration =

A

dehydration, hypoxic drive(COPD)
age
erythropoeitin secreting tumours

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7
Q

Causes of raised neutrophils

A

acute infection/inflammation, trauma or infarction

steroids

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8
Q

causes of raised eosinophils

A

parasite/allergy

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9
Q

causes of raised basophils

A

hypersensitivity

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10
Q

causes of raised monocytes

A

chronic infection
malignancy
AI

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11
Q

causes of raised lymphocytes

A

viral infection

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12
Q

Primary haemostasis =

A

platelets adhere and agglutinate

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13
Q

causes of low platelets =

A

liver disease, acute blood loss, coagulopathy, drug induced, AI

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14
Q

causes of high platelets =

A

acute blood loss, Fe deficiency, inflammation, malignancy

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15
Q

Secondary haemostasis =

A

Fibrin clot formation - coagulation cascade

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16
Q

2 pathways of coagulation cascade activation

A

Prothrombin time- TF/VII activated -> V/X -> thrombin -> fibrin
Activated partial thromboplastin time - VIII/IX activated -> V/X …

17
Q

VIII deficiency =

A

antihaemophic

18
Q

IX deficiency =

A

Christmas disease

19
Q

Increased ___ suggests increased fibrinolysis

A

D-dimers

20
Q

Breaks down plasminogen into plasmin

A

tPA - tissue plasminogen activator

1st step of fibrinolysis

21
Q

plasmin function

A

fibrin -> FDPs (fibrin degradation products including D-dimers)

JazRespiratory (18 decks)

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