Haem Pass Test Flashcards
Smear cels
CLL
What is the most common leukaemia in adults
B cell CLL
A high RDW indicates
A large variation in the size of RBCs (called anisocytosis)
Fibrin cloys are regraded by
Plasmin
The conversion of fibrinogen to fibrin is catalysed by
Thrombin
Does liver failure cause a prothrombotic state or bleeding?
Bleeding
RBCs that are hypochromic with central pallor
Haemoglobinopathy such as a thalassaemia
What does the vitamin b12 deficiency do to the spinal cord
Subacute combined degeneration of the cord
Bleeding gums can be caused by what vitamin deficiency
C - scurvy
Give 3 causes of a microcytic anaemia
IDA
Soderoblastic anaemia
Thalassameia
How would you investigate a thalassaemia
Haemoglobin electrophoresis
Haemophilia B
Clotting factor IX
X linked
Haemophilia A
Factor VIII
X linked
Cryoprecipitate can be used as an emergency in what type of haemophilia and why
A because it contains factor VIII
What is ITP
Antibodies attack the platelets
Why can haemochromatosis lead to polyuria and polydipsia
Pancreatic infiltration leading to DM
Why does haemochromatosis cause tanned skin
Melanin deposition
Why does haemochromatosis cause arthritis
Pyrophosphate arthropathy
Downs has an increased risk of which haem cancer
ALL
Treat a macrocytic anaemia with neuro involvement
1mg hydro coco alarmingly
Bcl2
Follicular lymphoma
Reduce the white cell count in CML
Leukapheresis
Raised MCV with hypersegmented neutrophils
Pernicious anaemia
Reticulocytosis witj schistocytes
Intravascular haemolysis
Sideroblasts and erythrocytes with basophilic staining
Lead poisoning
Hypochromia anisocytosis and poikilocytosis
IDA
Treat minor bleeds in haemophilia
Desmopressin and tranexamix acid
Treat major bleeds in haemophilia
Recombinant factor 8
Reduce risk of acute chest pain crisis in sickle cell with
Hydrocycatbamide (hydroxyurea)
DVT and pregnancy treatment course
Subcut LMWH
