Haem Pass Test

Question 1

Smear cels

Answer 1

CLL

Question 2

What is the most common leukaemia in adults

Answer 2

B cell CLL

Question 3

A high RDW indicates

Answer 3

A large variation in the size of RBCs (called anisocytosis)

Question 4

Fibrin cloys are regraded by

Answer 4

Plasmin

Question 5

The conversion of fibrinogen to fibrin is catalysed by

Answer 5

Thrombin

Question 6

Does liver failure cause a prothrombotic state or bleeding?

Answer 6

Bleeding

Question 7

RBCs that are hypochromic with central pallor

Answer 7

Haemoglobinopathy such as a thalassaemia

Question 8

What does the vitamin b12 deficiency do to the spinal cord

Answer 8

Subacute combined degeneration of the cord

Question 9

Bleeding gums can be caused by what vitamin deficiency

Answer 9

C - scurvy

Question 10

Give 3 causes of a microcytic anaemia

Answer 10

IDA
Soderoblastic anaemia
Thalassameia

Question 11

How would you investigate a thalassaemia

Answer 11

Haemoglobin electrophoresis

Question 12

Haemophilia B

Answer 12

Clotting factor IX

X linked

Question 13

Haemophilia A

Answer 13

Factor VIII

X linked

Question 14

Cryoprecipitate can be used as an emergency in what type of haemophilia and why

Answer 14

A because it contains factor VIII

Question 15

What is ITP

Answer 15

Antibodies attack the platelets

Question 16

Why can haemochromatosis lead to polyuria and polydipsia

Answer 16

Pancreatic infiltration leading to DM

Question 17

Why does haemochromatosis cause tanned skin

Answer 17

Melanin deposition

Question 18

Why does haemochromatosis cause arthritis

Answer 18

Pyrophosphate arthropathy

Question 19

Downs has an increased risk of which haem cancer

Answer 19

ALL

Question 20

Treat a macrocytic anaemia with neuro involvement

Answer 20

1mg hydro coco alarmingly

Question 21

Bcl2

Answer 21

Follicular lymphoma

Question 22

Reduce the white cell count in CML

Answer 22

Leukapheresis

Question 23

Raised MCV with hypersegmented neutrophils

Answer 23

Pernicious anaemia

Question 24

Reticulocytosis witj schistocytes

Answer 24

Intravascular haemolysis

Question 25

Sideroblasts and erythrocytes with basophilic staining

Answer 25

Lead poisoning

Question 26

Hypochromia anisocytosis and poikilocytosis

Answer 26

IDA

Question 27

Treat minor bleeds in haemophilia

Answer 27

Desmopressin and tranexamix acid

Question 28

Treat major bleeds in haemophilia

Answer 28

Recombinant factor 8

Question 29

Reduce risk of acute chest pain crisis in sickle cell with

Answer 29

Hydrocycatbamide (hydroxyurea)

Question 30

DVT and pregnancy treatment course

Answer 30

Subcut LMWH