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Oral board studying Prep book > GYN Oncology- Uterine cancer > Flashcards

GYN Oncology- Uterine cancer Flashcards

1
Q

What are the 2 types of endometrial cancer?

A

Type 1 endometrioid adenocarcinoma

Type 2 clear cell/papillary serous carcinoma

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2
Q

What is the most common uterine cancer?

A

Type 1 endometrioid adenocarcinoma

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3
Q

What is the most common cause for type 1 endometrioid cancer?

A

Unopposed estrogen

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4
Q

What is unique about type 2 clear cell/papillary serous uterine cancer?

A

Poor prognosis, high grade, focal pathology

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5
Q

What is the old terminology for benign hyperplasia?

A

Simple hyperplasia without atypia
Complex hyperplasia without atypia

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6
Q

What Is the old terminology for EIN?

A

Simple hyperplasia with atypia
Complex hyperplasia with atypia

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7
Q

What is the risk of concurrent uterine cancer with benign endometrial hyperplasia?

A

1%

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8
Q

What is the risk of uterine cancer with complex hyperplasia without atypia?

A

3%

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9
Q

What is the risk of uterine cancer with simple hyperplasia with atypia?

A

10%

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10
Q

What is the risk of uterine concurrent uterine cancer with complex hyperplasia with atypia?

A

30%

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11
Q

What is the treatment for EIN?

A

EIN is a premalignant lesion. Preferred treatment is surgical management can also treat with progestin therapy to thin the lining of uterus

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12
Q

What are the treatment options for EIN?

A

Mirena
Megace
Provera
Depo provera
Vaginal progesterone

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13
Q

What is the surveillance for treatment of EIN?

A

EMB every 3-6 months

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14
Q

What is the treatment for endometrial cancer?

A

Comprehensive surgical staging
Hysterectomy, BSO, lymph node dissection, pelvic washings

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15
Q

What is the most important prognostic factors for endometrial cancer?

A

Presence of extrauterine disease

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16
Q

What is the criteria for patient selection of medical management for endometrial cancer?

A

Premenopause and desire for future fertility

Poor candidate for major surgery due to co-morbidities

17
Q

What are the medical management options for endometrial cancer if you are an appropriate candidate?

A

Provera or megace
Progesterone IUD

18
Q

What is the surveillance for edometrial cancer after surgery?

A

History and Physical
Pelvic, vaginal and rectal exam every 3-6 months for 2 years then every 6 months for 3 years then annually

19
Q

How can tamoxifen therapy affect the uterus?

A

Can increase risk of endometrial proliferation, hyperplasia, polyp formation, uterine sarcoma

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