GYN Oncology Cervix Flashcards

1
Q

What is stage 1 Cervical cancer?

A

Carcinoma strictly confined to the cervix

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2
Q

What is stage 1A Cervical cancer?

A

Microscopic lesion less than or equal to 5mm of depth

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3
Q

What is stage 1B Cervical cancer?

A

Clinical lesion >5mm depth of invasion

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4
Q

What is stage 2 Cervical cancer?

A

Limited to upper 2/3 vagina without parametrial involvement

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5
Q

What is stage 2A Cervical cancer?

A

Beyond uterus, upper 2/3 vagina, not to pelvic wall

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6
Q

What is stage 2B Cervical cancer?

A

Extension to parametrium but not pelvic wall

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7
Q

What is stage 3 Cervical cancer?

A

Lower 1/3 vagina, entend to pelvic wall, +/- kidney affected

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8
Q

What is stage 3A Cervical cancer?

A

Lower 1/3 vagina, not to pelvic wall

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9
Q

What is stage 3B Cervical cancer?

A

Pelvic sidewall, +/- hydronephrosis or nonfunctioning kidney

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10
Q

What is stage 3C Cervical cancer?

A

Lymph nodes

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11
Q

What is stage 4 Cervical cancer?

A

Beyond true pelvis

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12
Q

What is stage 4A Cervical cancer?

A

Spread to adjacent pelvic organs

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13
Q

What is stage 4B Cervical cancer?

A

Spread to distant organs

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14
Q

What is the staging workup for cervical cancer?

A

Staging system is clinical
1. Physical exam
2. Cervical biopsy
3. endoscopy
4. Imaging
5. Pathology

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15
Q

What is the treatment for stage 1A1 cervical cancer without LVSI?

A

Cone+simple hysterectomy

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16
Q

What is the treatment for stage 1A1 cervical cancer with LVSI?

A

Radical hysterectomy + nodes

17
Q

What is the treatment for stage 1A2 cervical cancer?

A

Radical hysterectomy + nodes

18
Q

What is the treatment for stage 1B-2A cervical cancer?

A

Radical hysterectomy + nodes
or
Radiation + cisplatin

19
Q

What is the treatment for stage 2B-4B cervical cancer?

A

Radiation + cisplatin

20
Q

What is a radical hysterectomy?

A

Removal of uterus, cervix, tissue around the cervix and upper part of vagina

21
Q

What is a modified radical hysterectomy?

A

Removal of uterus, cervix and upper 1/3 of vagina

22
Q

If a patient is not a surgical candidate for cervical cancer what is the recommended treatment?

A

Chemoradiation

23
Q

How do you manage carcinoma of the cervix in pregnancy?

A

1st trimester= no change
2nd trimester= Terminate and treat
3rd trimester= Consider risks/benefits of prematurity vs delayed treatment

24
Q

What are the high risk HPV subtypes?

A

16,18,31,33,45,52,58

25
Q

Which high risk HPV subtype has the highest oncogenic potential and what is that potential?

A

16

Cause of 50% of cervical cancers