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NEC 3 > GULLAIN BARR SYNDROME > Flashcards

GULLAIN BARR SYNDROME Flashcards

1
Q

aka as ASCENDING POLYNEUROPATHIC PARALYSIS

A

Guillain-barre Syndrome

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2
Q

What is Guillain-barre syndrome?

A

an autoimmune attack on the peripheral nerve myelin

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3
Q

an autoimmune attack on the peripheral nerve myelin

A

Gullain-barre syndrome

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4
Q

Acute, rapid segmental demyelination of peripheral nerves and some cranial nerve

A

Gullain-barre syndrome

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5
Q

Pathophysiology of Guillain-barre syndrome

A

Acute, rapid segmental demyelination of peripheral nerves and some cranial nerve

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6
Q

A fatal form of polyneuritis

A

Guillain-Barre Syndrome

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7
Q

Guillain-barre syndrome fatal form

A

a fatal form of polyneuritis

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8
Q

Clinical Manifestations of Guillain-barre syndrome

A

-Symmetrical ascending paralysis with dyskinesia
- Hyporeflexia
-Paresthesias (numbness)

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9
Q

What is dyskinesia?

A

Inability to execute voluntary movements

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10
Q

Etiology of Guillain-barre syndrome

A

-Idiopathic
- Cell-mediated immunological reaction at the peripheral nerves
- Campylobacter jejuni
-Mycoplasma pneumonia
-Cytomegalovirus
-Epstein-barr virus
-Varicella-zoster virus
-Sensitization of T lymphocytes to the patient’s myelin

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11
Q

Cause of sensitization of T lymphocytes to the patient’s myelin

A

Results to myelin damage

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12
Q

What is demyelination?

A

-Transmission of nerve impulses is stopped or slowed down
-Denervation and atrophy of muscles

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13
Q

It is the most recognized

A

Campylobacter jejuni

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14
Q

Clinical Manifestations of Guillain-barre syndrome (Continuation)

A

-Symmetrical muscle weakness
-Neuropathic pain

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15
Q

What is symmetrical muscle weakness?

A

-key feature of GBS
- Ascending pattern (lower limbs then the upper extremities then the face and respiratory muscle)
- Leads to complete paralysis

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16
Q

What is neuropathic pain?

A

-prickling, burning type
- worse at night; decreases appetite

17
Q

Complications of Guillain-Barre Syndrome

A

-Respiratory failure
- UTI and URTI
- Paralytic ileus
- Deep vein thrombosis (DVT)
- Pulmonary embolism (PE)

18
Q

What is respiratory failure?

A
  • paralysis on the nerves at the thoracic area
    -major complication
19
Q

Diagnosis of Guillain-Barre Syndrome

A

-CSF Protein Test
- Single-fiber Electromyography Test

20
Q

What is CSF Protein Test?

A

-Increases on the 7th to 10th day
-15-60 milligrams per deciliter (mg/dl) is normal

21
Q

Nursing Management of Guillain-Barre Syndrome

A

-Ventilatory support
-Prevention of DVT and PE
-Intravenous immunoglobulin (IVIG)
-Monitor for skin breakdown

22
Q

Interventions of Intravenous Immunoglobulin

A

-Patients need to be well-hydrated
- Renal function monitoring

23
Q

How to prevent DVT and PE?

A

Administration of coagulants like HEPARIN

24
Q

How to monitor for skin breakdown?

A

Turning to sides

NEC 3 (16 decks)

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