CELIAC DISEASE & DIVERTICULAR DISEASE Flashcards
What is celiac disease?
-a unique autoimmune disease
-also known as gluten sensitive enteropathy
-damage to the small intestinal mucosa from ingestion of wheat, barley, rye and oats
a unique autoimmune disease
celiac disease
also known as gluten sensitive enteropathy
celiac disease
damaged to the small intestinal mucosa from ingestion of wheat, barley, rye, and oats
celiac disease
etiology of celiac disease
-genetic predisposition
-human leukocyte antigen (HLA) DQ2 & human leukocyte antigen (HLA) DQ8 positivity
-gluten ingestion
-immune-mediated response
cause chronic inflammation
gluten ingestion
gluten can be found in
wheat, barley, rye and oats
it also contains peptide called prolamines
gluten
water insoluble and difficult to digest
gluten
explain the characteristics of gluten
-found in wheat, rye, barley and oats
- contain peptide called prolamines
- water insoluble and difficult to digest
Clinical manifestations of celiac disease
-foul-smelling diarrhea
-steatorrhea
-flatulence
-abdominal distention
- osteoporosis
complications of celiac disease
Autoimmune disease
1. rheumatoid arthritis
2. type 1 diabetes mellitus
3. thyroid disease
What is the confirmatory criteria (diagnosis) of celiac disease?
- there is histological evidence of the disease following biopsy from the small intestine.
- the symptoms and histological evidence disappear when a person eats a gluten-free diet
Management of celiac disease
-Corticosteroid therapy
- gluten-free diet
What medication contains a gluten?
Olmesartan (Benicar)
this can be combined by gluten-free diet if gluten-free diet isn’t effective alone
corticosteroid therapy
what are the gluten-free diet?
wheat, barley, rye and oats
a condition of having a small pockets or pouches in the inside wall of the intestine
diverticular disease
what is diverticular disease?
a condition of having a small pouches or pockets in the inside wall of the intestine.
what is diverticulum?
an outpouching of the mucosa through the circular smooth muscle of the intestinal wall