CELIAC DISEASE & DIVERTICULAR DISEASE Flashcards

1
Q

What is celiac disease?

A

-a unique autoimmune disease
-also known as gluten sensitive enteropathy
-damage to the small intestinal mucosa from ingestion of wheat, barley, rye and oats

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1
Q

a unique autoimmune disease

A

celiac disease

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2
Q

also known as gluten sensitive enteropathy

A

celiac disease

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3
Q

damaged to the small intestinal mucosa from ingestion of wheat, barley, rye, and oats

A

celiac disease

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4
Q

etiology of celiac disease

A

-genetic predisposition
-human leukocyte antigen (HLA) DQ2 & human leukocyte antigen (HLA) DQ8 positivity
-gluten ingestion
-immune-mediated response

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5
Q

cause chronic inflammation

A

gluten ingestion

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6
Q

gluten can be found in

A

wheat, barley, rye and oats

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7
Q

it also contains peptide called prolamines

A

gluten

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8
Q

water insoluble and difficult to digest

A

gluten

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9
Q

explain the characteristics of gluten

A

-found in wheat, rye, barley and oats
- contain peptide called prolamines
- water insoluble and difficult to digest

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10
Q

Clinical manifestations of celiac disease

A

-foul-smelling diarrhea
-steatorrhea
-flatulence
-abdominal distention
- osteoporosis

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11
Q

complications of celiac disease

A

Autoimmune disease
1. rheumatoid arthritis
2. type 1 diabetes mellitus
3. thyroid disease

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12
Q

What is the confirmatory criteria (diagnosis) of celiac disease?

A
  1. there is histological evidence of the disease following biopsy from the small intestine.
  2. the symptoms and histological evidence disappear when a person eats a gluten-free diet
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13
Q

Management of celiac disease

A

-Corticosteroid therapy
- gluten-free diet

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14
Q

What medication contains a gluten?

A

Olmesartan (Benicar)

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15
Q

this can be combined by gluten-free diet if gluten-free diet isn’t effective alone

A

corticosteroid therapy

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16
Q

what are the gluten-free diet?

A

wheat, barley, rye and oats

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17
Q

a condition of having a small pockets or pouches in the inside wall of the intestine

A

diverticular disease

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18
Q

what is diverticular disease?

A

a condition of having a small pouches or pockets in the inside wall of the intestine.

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19
Q

what is diverticulum?

A

an outpouching of the mucosa through the circular smooth muscle of the intestinal wall

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20
Q

an outpouching of the mucosa through the circular smooth muscle of the intestinal wall

A

diverticulum

21
Q

what are the 2 forms of diverticular disease

A
  1. diverticulosis
  2. diverticulitis
22
Q

multiple non-inflamed

A

diverticulosis

23
Q

a complication of diverticulosis

A

diverticulitis

24
diverticula are present
diverticulosis
25
patient is free of symptoms
diverticulosis
26
may have alternating periods of constipation and diarrhea
diverticulosis
27
describe the characteristics of diverticulosis
-multiple noninflamed -diverticula are present -patient is free of symptoms - may have alternating periods of constipation and diarrhea
28
describe the characteristics of diverticulitis
- inflammation of the diverticula - occurs when the pocket becomes inflamed or swollen
29
diverticulosis occurs at what age?
50 years of age
30
Clinical manifestations of diverticulosis
-usually asymptomatic - crampy abdominal pain -relived by passage of flatus -alternating diarrhea & constipation
31
Clinical manifestations of diverticulitis
-perforation of the peritonitis -abscess and fistula formation -bowel obstruction -bleeding
32
stops spontaneously
bleeding
33
describe the presence of steatorrhea?
excessive fats in the feces
34
the diagnosis of diverticular disease
1. CT scan with oral contrast 2. Fecal occult blood test 3. Barium enema 4. Colonoscopy
35
test of choice for diverticulosis
ct scan with oral contrast
36
what is fecal occult blood test
look for blood in the stool
37
determine narrowing of obstruction in the colonic lumen
barium enema
38
what is barium enema?
determine narrowing of obstruction in the colonic lumen
39
the purpose of colonoscopy
to rule out possible hidden of polyps or lesions
40
to rule out possible hidden of polyps or lesions
colonoscopy
41
barium enema & colonoscopy are contraindicated in patient who have
contraindicated in patient who have acute diverticulitis
42
why barium enema & colonoscopy is contraindicated in patients with acute diverticulitis
because of the possibility of perforation and peritonitis
43
Surgical Management of Diverticular Disease
1. resection with temporary diverting colostomy 2. reanastomosis after the colon has healed.
44
what is the management for diverticular disease?
-high fiber diet (during nonasymptomatic periods) - dietary fiber supplements (during nonasymptomatic periods) - stool softeners - clear liquid diet - oral antibiotics
45
what's the management if overweight?
weight reduction
46
What's the purpose of NPO status?
to allow the colon to rest and the inflammation to subside
47
What needs to be watch out for in acute diverticulitis?
WOF symptoms of peritonitis
48
Possible colon resection
- perforation - obstruction - hemorrhage
49
patient with acute diverticulitis must have
bed rest