CELIAC DISEASE & DIVERTICULAR DISEASE Flashcards

1
Q

What is celiac disease?

A

-a unique autoimmune disease
-also known as gluten sensitive enteropathy
-damage to the small intestinal mucosa from ingestion of wheat, barley, rye and oats

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1
Q

a unique autoimmune disease

A

celiac disease

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2
Q

also known as gluten sensitive enteropathy

A

celiac disease

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3
Q

damaged to the small intestinal mucosa from ingestion of wheat, barley, rye, and oats

A

celiac disease

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4
Q

etiology of celiac disease

A

-genetic predisposition
-human leukocyte antigen (HLA) DQ2 & human leukocyte antigen (HLA) DQ8 positivity
-gluten ingestion
-immune-mediated response

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5
Q

cause chronic inflammation

A

gluten ingestion

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6
Q

gluten can be found in

A

wheat, barley, rye and oats

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7
Q

it also contains peptide called prolamines

A

gluten

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8
Q

water insoluble and difficult to digest

A

gluten

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9
Q

explain the characteristics of gluten

A

-found in wheat, rye, barley and oats
- contain peptide called prolamines
- water insoluble and difficult to digest

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10
Q

Clinical manifestations of celiac disease

A

-foul-smelling diarrhea
-steatorrhea
-flatulence
-abdominal distention
- osteoporosis

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11
Q

complications of celiac disease

A

Autoimmune disease
1. rheumatoid arthritis
2. type 1 diabetes mellitus
3. thyroid disease

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12
Q

What is the confirmatory criteria (diagnosis) of celiac disease?

A
  1. there is histological evidence of the disease following biopsy from the small intestine.
  2. the symptoms and histological evidence disappear when a person eats a gluten-free diet
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13
Q

Management of celiac disease

A

-Corticosteroid therapy
- gluten-free diet

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14
Q

What medication contains a gluten?

A

Olmesartan (Benicar)

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15
Q

this can be combined by gluten-free diet if gluten-free diet isn’t effective alone

A

corticosteroid therapy

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16
Q

what are the gluten-free diet?

A

wheat, barley, rye and oats

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17
Q

a condition of having a small pockets or pouches in the inside wall of the intestine

A

diverticular disease

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18
Q

what is diverticular disease?

A

a condition of having a small pouches or pockets in the inside wall of the intestine.

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19
Q

what is diverticulum?

A

an outpouching of the mucosa through the circular smooth muscle of the intestinal wall

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20
Q

an outpouching of the mucosa through the circular smooth muscle of the intestinal wall

A

diverticulum

21
Q

what are the 2 forms of diverticular disease

A
  1. diverticulosis
  2. diverticulitis
22
Q

multiple non-inflamed

A

diverticulosis

23
Q

a complication of diverticulosis

A

diverticulitis

24
Q

diverticula are present

A

diverticulosis

25
Q

patient is free of symptoms

A

diverticulosis

26
Q

may have alternating periods of constipation and diarrhea

A

diverticulosis

27
Q

describe the characteristics of diverticulosis

A

-multiple noninflamed
-diverticula are present
-patient is free of symptoms
- may have alternating periods of constipation and diarrhea

28
Q

describe the characteristics of diverticulitis

A
  • inflammation of the diverticula
  • occurs when the pocket becomes inflamed or swollen
29
Q

diverticulosis occurs at what age?

A

50 years of age

30
Q

Clinical manifestations of diverticulosis

A

-usually asymptomatic
- crampy abdominal pain
-relived by passage of flatus
-alternating diarrhea & constipation

31
Q

Clinical manifestations of diverticulitis

A

-perforation of the peritonitis
-abscess and fistula formation
-bowel obstruction
-bleeding

32
Q

stops spontaneously

A

bleeding

33
Q

describe the presence of steatorrhea?

A

excessive fats in the feces

34
Q

the diagnosis of diverticular disease

A
  1. CT scan with oral contrast
  2. Fecal occult blood test
  3. Barium enema
  4. Colonoscopy
35
Q

test of choice for diverticulosis

A

ct scan with oral contrast

36
Q

what is fecal occult blood test

A

look for blood in the stool

37
Q

determine narrowing of obstruction in the colonic lumen

A

barium enema

38
Q

what is barium enema?

A

determine narrowing of obstruction in the colonic lumen

39
Q

the purpose of colonoscopy

A

to rule out possible hidden of polyps or lesions

40
Q

to rule out possible hidden of polyps or lesions

A

colonoscopy

41
Q

barium enema & colonoscopy are contraindicated in patient who have

A

contraindicated in patient who have acute diverticulitis

42
Q

why barium enema & colonoscopy is contraindicated in patients with acute diverticulitis

A

because of the possibility of perforation and peritonitis

43
Q

Surgical Management of Diverticular Disease

A
  1. resection with temporary diverting colostomy
  2. reanastomosis after the colon has healed.
44
Q

what is the management for diverticular disease?

A

-high fiber diet (during nonasymptomatic periods)
- dietary fiber supplements (during nonasymptomatic periods)
- stool softeners
- clear liquid diet
- oral antibiotics

45
Q

what’s the management if overweight?

A

weight reduction

46
Q

What’s the purpose of NPO status?

A

to allow the colon to rest and the inflammation to subside

47
Q

What needs to be watch out for in acute diverticulitis?

A

WOF symptoms of peritonitis

48
Q

Possible colon resection

A
  • perforation
  • obstruction
  • hemorrhage
49
Q

patient with acute diverticulitis must have

A

bed rest