CEREBROVASCULAR DISORDERS Flashcards
The functional abnormality of the CNS when the normal blood supply to the brain is disrupted
CEREBROVASCULAR DISORDERS
What is cerebrovascular disorders
The functional abnormality of the CNS when the normal blood supply to the brain is disrupted
What is stroke?
The primary type of CVD
Types of stroke
-Ischemic stroke
- Hemorrhagic stroke
Aka as cerebrovascular accident
Ischemic stroke
Brain attack
Ischemic stroke
Sudden loss of function resulting from disruption of the blood supply to a part of the brain
Ischemic stroke
What is ischemic stroke?
-Aka as cerebrovascular accident
-Brain attack
-Sudden loss of function resulting from disruption of the blood supply to a part of the brain
Types of ischemic stroke
- large artery thrombotic strokes
- small penetrating artery thrombotic strokes
- Cardiogenic embolic strokes
- Cryptogenic stroke
What is large artery thrombotic stroke?
Caused by atherosclerotic plaques in the large blood vessels of the brain causing infarction
What is small penetrating artery thrombotic strokes?
affect one or more vessels and are the most common type of ischemic stroke; leaves a cavity after death or infarcted tissue
What is cardiogenic embolic strokes?
Associated with cardiac dysrhythmias, usually atrial fibrillation
What is cryptogenic stroke?
-have no known cause
- Also known as “stroke of unknown cause
-have no known cause
- Also known as “stroke of unknown cause
Cryptogenic stroke
Caused by atherosclerotic plaques in the large blood vessels of the brain causing infarction
large artery thrombotic stroke
affect one or more vessels and are the most common type of ischemic stroke; leaves a cavity after death or infarcted tissue
small penetrating artery thrombotic strokes
Associated with cardiac dysrhythmias, usually atrial fibrillation
cardiogenic embolic strokes
What is the main issue of the large artery thrombotic stroke?
Lack of oxygen-ischemia- lead to necrosis
a cellular metabolic event
Ischemic cascade
occurs after blood obstruction
Ischemic cascade
in ischemic cascade how many blood decreases?
blood decrease less than 25 ml per 100g of blood per minute
blood decrease less than 25 ml per 100 mg of blood per minute
ischemic cascade
Aerobic respiration of neurons fails
ischemic cascade
switches to anaerobic respiration
ischemic cascade
it generates large amounts of lactic acid, causing a change in the PH
anaerobic respiration
describe the characteristics of ischemic cascade
-a cellular metabolic event
-occurs after blood obstruction
-blood decrease less than 25 ml per 100 mg of blood per minute
-Aerobic respiration of neurons fails
-switches to anaerobic respiration
An area of low cerebral blood flow
Penumbra region
may be salvaged with timely intervention
Penumbra region
increase in intracellular calcium and the release of glutamate
Penumbra region
activate a number of damaging pathways; extends the stoke
glutamate
Characteristics of penumbra region
-An area of low cerebral blood flow
- May be salvaged with timely intervention
- increase in intracellular calcium and the release of glutamate
Toxic to brain if it increases and leads to necrosis
Glutamate
due to anaerobic activity
Glutamate
Memory enhancement
Glutamate
Characteristics of glutamate
-memory enhancement
- toxic to brain if it increases and leads to necrosis
- due to anaerobic activity
-memory enhancement
Clinical Manifestations of Ischemic stroke
MOTOR LOSS
-hemiplegia
-hemiparesis
COMMUNICATION LOSS
-Dysarthria
-Dysphasia
-Apraxia
PERCEPTUAL DISTURBANCES
-visual-perceptual disturbances
-homonymous hemianopsia
SENSORY LOSS
-Loss of Proprioception
-Agnosia
Loss of voluntary control over motor movements
Motor loss
What is motor loss?
Loss of voluntary control over motor movements
What is hemiplegia?
-Paralysis of one side of the body
-caused by a lesion of the opposite side of the brain
What is hemiparesis?
-weakness of one side of the body
-refer to pt
Paralysis of one side of the body
Hemiplegia
Weakness of one side of the body
Hemiparesis