GRAM-POSITIVE ORGANISMS III Flashcards
endospore enters at some minor skin lessions and occurs 90% cases in humans
Cutaneous anthrax
by ingestion of undercooked food containing anthrax endospore (rare in humans)
Gastrointestinal anthrax
endospore inhaled into lungs
most dangerous form of anthrax in humans
Inhalation Anthrax
Food poisoning (Fried rice syndrome)
Bacillus cereus
heat stable toxin
Vomitus form
heat labile toxin
Diarrheal form
isolated from debrided tissue of a compound fracture in 7 year old Margaret Tracy
Bacillus subtilis
– causes UTI, wound infection
– produces “bacitracin”
Bacillus subtilis
- anaerobic, Gram-positive bacteria
- inhabit soils and the intestinal tracts of animals, including humans
- This genus includes several significant human pathogens, including the causative agents of botulism and tetanus.
clostridium
causes botulism(rare but serious condition caused by a toxin that attacks the body’s nerves
Clostridium botulinum
most common Clostridium botulinum
Infant botulism
– tetanus
– acquired through wound from soil
Clostridium tetani
gas gangrene (non healing wound with formation of gas-bubbling/foul odor
clostridium perfringens
clostridium perfringens tx:
amputation, hyperbaric O2 chamber, maggot therapy
– “Kleb-Loeffler’s baccilus”
– causes Diphtheria (Bull-neck appearance)
Corynebacterium diphtheria