acellular microbes 2 Flashcards
lesions of upper body
Herpes simplex virus 1 (HSV-1)
lesions of lower body
Herpes simplex virus 2
prevent organs from working properly
Human cytomegalovirus
caused by HHV-8
Kaposi’s sarcoma
kissing disease
Epstein-Barr virus
chickenpox
Varicella zoster virus
“sixth disease” occurs in infants/children induces seizures
Human herpesvirus 6 (HHV-6)
“sixth disease” mild and self-limited infection in children
Human herpesvirus 7 (HHV-7)
enveloped DNA viruses:
Hepadnaviridae
Herpesviridae
Poxviridae
viruses are pieces of host cell RNA/DNA
that have escaped from living cells
ESCAPED GENE THEORY
Three major theories to explain origin
of viruses:
COEVOLUTION THEORY
RETROGRADE EVOLUTION THEORY
ESCAPED GENE THEORY
viruses evolved from free-living prokaryotes
RETROGRADE EVOLUTION THEORY
viruses originated in the primordial soup
COEVOLUTION THEORY
Three categories based on shape:
Icosahedron bacteriophages
Filamentous bacteriophages
Complex bacteriophages
– the viruses that infects bacteria
– obligate intracellular pathogens (cannot reproduce outside cell host
BACTERIOPHAGES
almost spherical shape with 20 triangular facets
Icosahedron bacteriophages
long tubes formed by capsid proteins assembled into helical structure. Up to 900nm long
Filamentous bacteriophages
icosahedral heads attached to helical tails.
Complex bacteriophages
simple replication cycle that ends with the destruction(lysis)
LYTIC CYCLE
causes lytic cycle
VIRULENT BACTERIOPHAGES
do not immediately initiate lytic cycle
TEMPERATE PHAGES
Steps in Multiplication of Bacteriophages(Lytic Cycle):
ATTACHMENT (Adsorption)
PENETRATION
BIOSYNTHESIS
ASSEMBLY
RELEASE
the phage attaches to a protein
ATTACHMENT (Adsorption)
the phage injects its DNA into the bacterial cell
PENETRATION