Gonadal Development Flashcards
The embryo goes through 3 attempts to form excretory ducts. What are they?
Pronephros, mesonephros, and metanephros
Is pronephros the first attempt the embryo makes? How long is its lifespan?
Yes! Short-lived & contributes pronephric duct
Is mesonephros the second attempt of the embryo to make an excretory duct? & what’s its lifespan
Yes! Its lifespan is substantial & it adopts the paranephic ducts. Becomes mesonephric duct
What is the metanephros
Adult kidney
SAME FOR MALES & FEMALES: Where do primordial germ cells populate during early embryonic development?
Yolk sac to protect them from differentiation processes. They eventually migrate back into embryo through parts of GIT
Where do primordial follicles migrate to?
From yolk sac to genital ridge which is adjacent to mesonephric kidney
Where is the genital ridge located relative to mesonephros?
Medial
MALES: at the genital ridge, coelomic epithelium develops into cell cords which penetrates
Genital ridge & take primordial germ cells with them
MALES: cell cords form
Tubules - this means inside of cell cords are invested with primordial germ cells
MALES: Primordial germ cells start to develop
Sertoli cells & germinal epithelium
In males, the seminal epithelium thickens and forms CT known as
Tunica albuginea
MALES: does the paranephric duct deteriorate>
Yes
MALES: do cell cords attach to the rete testis?
Yes
MALES: What happens when the mesonephros starts to deteriorate?
Tubules also begin to deteriorate except about 12. These provide connectivity from mesonephric duct to rete testis
MALES: The tubules change shape so that
Their origin and termination are located at the rete testis
MALES: Rete testis forms communication with
mesonephric tubules
MALES: is there a thick tunica albuginea
Yes
MALES: tubules mature into
Efferent ductules which connect to duct of epididymus
FEMALES: cell cords start to fragment and end up as
Clusters of cells in mesenchyme of genital ridge
FEMALES: primordial cells keep dividing by
Mitosis
FEMALES: Clusters of cells break down so that each cell is
A germ cell Invested with single layer of coelomic epithelium cells to eventually form granulosa cells