glucose metabolism just notes Flashcards
why is all the energy in glucose not released in one go?
cannot utilise heat
no single reaction of metabolism need that much energy
enzymes only effect small changes
step 1
formation of a covalent bond (——— bond) between the substrate and the enzyme (—————– 3 phosphate)
thioether
glyceraldehyde 3 phosphate
step 2
——— of the thioether bond to form a thioether bond using ——- to perform the oxidation
hydrolysis of thioether bonds is ————-
oxidation
NAD+
exergonic
step 3
the cleavage of the thioether bond supplies the ——- to drive the ————- —————–
the product a ———— is released from the enzyme
energy
endergonic phosphorylation
phophoaldehyde
red blood cells cant get any energy so rbc need to ——— energy by anaerobic means
regenerate
pyruvate is converted to lactate by
lactate dehydrogenase
pyruvate - acetyl CoA
pyruvate dehydrogenase complex
pyruvate - acetyl CoA
CoA-sh +NAD+
out:
NADH
CO2
ATP couples both
exergonic and endergonic reactions
pyruvate to OAA
atp-adp
HCO3-
Pyruvate carboxylase
OAA to Phosphoenolpyruvate
GTP- GDP
Phosphoenolpyruvate carboxykinase