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biochem 2 > fatty acids > Flashcards

fatty acids Flashcards

1
Q

what are FA

A

long hydrocarbon chains

insoluble in water

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2
Q

saturated

A

No double bonds

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3
Q

monounsaturated

A

1 double bond

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4
Q

polyunsaturated

A

more then 2 double bonds

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5
Q

conversion, Increases chain length by 2 carbons

A

Elongase

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6
Q

conversion, removal of a double bond and adding a extra bond and a H+

A

desaturase

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7
Q

desaturation doesnt work below omega 9 what what do we have to do?

A

intake omega 3,6 via the diet

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8
Q

neutral fats what are they?

A

stores of fats

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9
Q

Neutral fats, triglyceride (tg)—— ?

diglyceride-

A

triacylglycerol

diacylglycerol

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10
Q

Activation, TAGs are re-esterified in the

A

gut mucosa

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11
Q

Activation, FA + CoA + ATP —– Acyl-coa + H2O + AMP +PPi

A

acyl CoA synthetase

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12
Q

Activation, attachment of glycerol to 2 more Acyl-coa using——– losing 2 CoA-h

A

Acyltransferase

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13
Q

lipoproteins why are they used

A

triglycerides are packed into them for transport in blood they are too hydrophobic otherwise

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14
Q

transport, from gut to tissues

A

chylomicrons

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15
Q

what are chylomicrons

3 answers

A

water soluble
a mixture of lipids and apolipoproteins
phospholipid and cholesterol outer layer

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16
Q

what is inside chylomicrons

3 answers

A

triglycerides, cholesterol and fat soluble lipids

17
Q

so triacylglycerides are digested by ——— to create a monoacylglyceride and FA so they can get through the ———— then it goes into ————

A

lipase
bilayer
chylomicrons

18
Q

what do tissues have to release the FA into cells from lipoproteins?

A

they have lipoprotein lipase which cleaves of FA so they can enter the cell

19
Q

what is a chylomicron calledafter it has offloaded all the TAGS and how is it removed

A

a remnant, removed from the circulation by the liver

20
Q

TG synthesis, dihydrogyacetone phosphate ——— glycerol 3 phosphate

A

glycerol 3 phosphate dehydrogenase

21
Q

G-3-P —— lysophosphatidic acid

A

Glycerol 3 phosphate acyltransferase

22
Q

lysophosphatidic acid—— phosphatidic acid

A

1-acyl glycerol 3 phosphate acyltransferase

23
Q

phosphatidic acid —— diacylglycerol

A

phosphatidic acid phosphatase

24
Q

diacylglycerol ——– triacylglycerol

A

diacylglycerol acyltransferase

25
Q

FA catabolism, 3 steps

A

mobilisation
activation
Beta oxidation

biochem 2 (18 decks)

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