Gluconeogenesis Flashcards

1
Q

in the absence of——, most of the body use——— ————–for energy

A

insulin

Fatty acids

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2
Q

brain and RBC only use

A

Glucose

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3
Q

pyruvate to PEP (1st step)
Atp-ADP
HCO3- to HOCO2

A

use biotin prosthetic group
pyruvate carboxylase
forms OAA

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4
Q

pyruvate to PEP (2nd step)
OAA + GTP —- PEP + GDP + CO2
where does it happen

A

PEP carboxykinase

cytoplasm

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5
Q

irreversible reaction 2
fructose 1,6 bisphosphate + H2O —- F-6-p + Pi
type of reaction?
where?

A

Fructose 1,6 bisphosphotase
hydrolysis
cytoplasm

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6
Q

irreversible reaction 3

G-6-P + H2O ——- Glucose + Pi

A

Glucose 6 phosphotase

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7
Q

what cant G-6-P do?

A

cant leave the bilayer

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8
Q

we dont have Glucose 6 phosphotase in what part of the body?

A

muscles

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9
Q

problems with gluconeogenesis

A

no stores of pyruvate to maintain gluconeogenesis

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10
Q

solution to problem

A

lactate cori cycle

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11
Q

lactate cori cycle

glucose – pyruvate – latcate

A

lactate —–(LDH)—— pyruvate—–glucose

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12
Q

glucogenic amino acids

what is used to make glucose in the muscles?

A

alanine

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13
Q

muscle catabolism releases

A

alanine into blood the converted into pyruvate

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14
Q

glycerol can be converted into

A

dihydroxyacetone phosphate

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15
Q

dihydroxyacetone phosphate can be attached to

A

glyceraldehyde 3 phosphate to produce F-1,6-bisp

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16
Q

Amino acids can be added together to form—-, which is used to convert pyruvate to—–

A

OAA

PEP