Glossary Flashcards
Abscess
inflammatory nodule containing pus
Acanthosis
Hyperplasia of the PCL causing an increase in epidermal thickness
Adnexae
structures making up hair, nails and glands
Alopecia
loss of hair
Allergen
Antigens that induce allergic reactions
Anagen
Growth phase of hair
Anaphylaxis
Severe type 1 hypersensitivity
Annular
ring shaped
Antibody
protein generated in response to an antigen
Apocrine
type of sweat gland
Atopy
hypersensitivity with genetic predisposition
Atrophy
wasting / shrinking of cells, tissues or organ
Auspitz sign
pinpoint bleeding seen when scale of psoriasis is removed
Blackhead
open comedone
dark sebum and keratin plug at pilosebaceous unit
Bulla
> 5mm
fluid filled blister
Burrow
excavation in KL housing a parasite
Cafe au lait spots
pigmented patches seen in neurological conditions e.g. neurofibromatosis (overgrowth of nerve endings)
Callus
hypertrophy of KL in localised areas usually hands and feet
Carbuncle
cluster of furuncles causing skin necrosis
Carcinoma
malignant growth of epithelial cells
Carcinoma in situ
malignant potential but not crossed the basement membrane
Catagen
involuting phase of hair growth
Cellulitis
inflammation of the dermis
Cold sore
herpes simplex infection usually of lips
Comedone
"blackhead" = open "whitehead" = closed
Compound naevus
Collection of benign melanocytes at DEJ and dermis
Corn
cortical thickening of KL pointing into dermis
painful
Crust
dried exudate on skin
Cryotherapy
freezing treatment - liquid nitrogen
Cyst
nodule containing semisolid material
Depigmentation
removal of pigment
Dermatitis
aka eczema
inflammatory process involving epidermis
Dermatome
area of skin supplied by a single spinal root
Desmosome
structure connecting keratinocytes
Drug eruption
skin reaction caused by medication
Ecchymosis
“bruising”
red/purple patch of haemorrhage in skin or mucous membrane
Eccrine
type of sweat gland
Elastosis
degeneration of elastic tissue in dermis
Erosion
break in epidermis
does not reach dermis
Erythroderma
redness over majority of body
Excoriation
superficial abrasion due to scratching
Fissure
linear split in skin
Follicle
depressed cavity
Freckle
pigmented macule by melanin production
Furuncle
pus filled nodule by bacterial infection of hair follicle
Genodermatosis
genetically determined skin disease
Guttate
drop shaped
Hamartoma
tumour like but non-neoplastic overgrowth of tissue with disordered structure
Hirsutism
excessive male pattern hair growth
Hyperhidrosis
excessive sweating
Hyperkeratosis
increased thickening of KL
Hyperpigmentation
abnormally increased pigmentation
Hyperplasia
increase in cell number
Hypersensitivity
exaggerated immune response to a foreign agent
Hypertrichosis
excessive hair growth in a non-androgenic pattern
Hypertrophic scar
enlarged and thickened scar
Hypertrophy
increase in cell size
Ichthyosis
dry, roughened and scaly skin
Keloid
elevated scar enlarging beyond wound margins composed of excessive collagen
Keratolysis
dissolution of KL
Keratosis
horn like thickening of skin
Lanugo
fine hair on babies
Lentigo
pigmented macule
Leukonychia
white discolouration of nails
Lichenification
chronic thickening of skin with increased skin markings
Macerate
soften by wetting or soaking
Macule
flat lesion / non palpable
<1cm
Milia
small white cyst containing keratin
Munro’s abscess
microabscesses in parakeratotic layer in psoriasis
Naevus
stable malformation of the skin
Necrosis
pathological cell death
Neurofibroma
tumour of Schwann cells
Nodule
Solid elevation of the skin
>5mm
Onycholysis
separation of nail from nail bed
Panniculitis
inflammation of subcutaneous fat layer
Papilloma
nipple like projection from skin surface
Papule
solid elevation of the skin
<5mm
Parakeratosis
nuclei retained in keratinocytes in KL
Paronychia
inflammation of tissue around nails
Petechia
Minute haemorrhagic spot
Pilar
relating to hair
Pitted nails
small depression of nail plate
Plaque
slightly raised flat lesion
>2cm
Poikiloderma
combination of telangiectasia, pigmentation and atrophy in the skin
Pore
opening of a sweat duct
Porphyria
group of diseases caused by abnormalities of porphyrin metabolism
Pruritis
itch
Psoriasiform
like psoriasis
Purpura
haemorrhage into tissues causing red/purple discolouration
non-blanching
Pustule
raised lesion containing pus
RAST
Radioallergosorbent test to detect specific IgE antibodies
Scab
crust on superficial wounds
Sclerosis
induration or hardening
Seborrhoea
excessive secretion of sebum
Sebum
greasy product of sebaceous glands
Sinus
cavity or channel
Spongiosis
intercellular oedema of epidermis
Squamous cell
flat cells
Striae
atrophic line in skin due to changes in connective tissue
aka stretch marks
Telangiectasia
visible dilatation of dermal blood vessels
Telogen
resting stage of hair growth
Ulcer
break into dermis
Ungual
relating to nails
Urticaria
wheals and itching
Vasculitis
necrotising inflammation of blood vessels
Vesicle
small blister containing clear fluid
<5mm
Weeping
exudation of clear serum from inflamed skin
Wheal
transitory papule or plaque of dermal oedema
Whitehead
closed comedone
Wickham’s striae
pale reticular network on surface of lesions of lichen planus
Wood’s lamp
emits long wavelength UV light producing immunofluorescence in certain conditions e.g. fungal infection