Dermatitis / Eczema Flashcards
what is seen on a biopsy of dermatitis
spongiosis and inflammatory cell infiltrate
4 hallmark symptoms of eczema
itchy
erythematous
ill defined
scaly
symptoms of acute eczema
vesicles
erythematous
oedema and weeping
ooze, scale, crust
symptoms of chronic eczema
lichenification
excoriations
elevated plaques
increased scaling
There are many different subtypes of eczema / dermatitis, true or false
true
What type of hypersensitivity is contact allergic dermatitis (CAD)
type 4 - T cell mediated
delayed
examples of allergens in CAD
nickel, creams, plants, latex, fragrance…
what investigation can be done for CAD and what is involved
patch testing
patches with different chemicals are placed on the patients back and removed after 48 hours
Check for results after 96 hours
what is irritant contact dermatitis (ICD)
non-specific physical irritation rather than an allergy
CAD and ICD are hard to differentiate, true or false
true
examples of irritants in ICD
soap, urine, water, cleaning products, chemicals, detergents
in a nappy rash and ICD, there is flexural involvement, true or false
false, there is flexural sparing
involvement of flexures would suggest a fungal infection
what is the pathology behind atopic eczema
filaggrin mutation
symptoms of atopic eczema
itch dry skin scaly erythema poorly defined edges impaired QoL
eczema commonly affects the flexures/extensors?
flexures
cubital fossae, behind knees, earlobes, ankles, wrists