gland secretions Flashcards

1
Q

Secretion involves 3 distinct cellular activities:

A
  • uptake of simple materials from the extracellular fluid
  • processing of these within the cell: produce a more complex product
  • release, or transport, of these products
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2
Q

what is excretion

A

which is the removal of waste products

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3
Q

can all cells secrete

A

yes

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4
Q

two functional types of glands

A
  • Exocrine: release secretory products onto surface epithelium via
    a duct
  • eg sweat glands, salivary glands
  • Endocrine: no duct connecting secretory portion to surface epithelium, secrete products directly into blood or lymph (hormones)
  • eg pancreas, thyroid gland
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5
Q

what forms multicellular exocrine and endocrine galnds

A

epithelial sheets

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6
Q

3 modes of secretion in exocrine glands

A
  • Merocrine (eccrine)
  • Apocrine
  • Holocrine
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7
Q

merocrine (eccrine) secretion
(exocrine)

A
  • vesicles are released via exocytosis when the vesicle
    membranes fuse with the cell membrane
  • most common form of secretion
  • e.g. some sweat glands, salivary glands
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8
Q

what is the most common form of secretion

A

Merocrine (eccrine)

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9
Q

Apocrine secretion

(exocrine)

A
  • secretory vesicles accumulate at the apical portion of cell
  • mass of cytoplasm and vesicles is then pinched off
  • e.g. mammary gland, some sweat glands
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10
Q

holocrine secretion

(exocrine)

A
  • secretory products accumulate and the cell ruptures
  • death of cell
  • e.g. sebaceous glands
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11
Q

A further classification of glands is based on structure:

A

unicellular and multicellular

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12
Q

unicellular glandular structure

A
  • goblet cells of digestive & respiratory tracts
  • the only type of unicellular gland
  • secrete mucin –> mucous
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13
Q

most glands are multi or uni cellular

A

multicellular

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14
Q

goblet cells are found where

A

amongst columnar cells of epithelium
* digestive tract
* respiratory tract

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15
Q

in goblet cells there is Expanded apical portion (theca) contains

A

mucigen droplets

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16
Q

in goblet cells mucigen released by ____ secretion

A

merocrine

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17
Q

what makes up mucous

A

mucigen + H2O

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18
Q

describe nucleus in goblet cells

A

basal nucleus

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19
Q

describe cytoplasm in goblet cells

A
  • Basophilic cytoplasm
  • rER & free ribosomes
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20
Q

Multicellular Exocrine Glands: Secretions discharged onto epithelial surface via

A

ducts

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21
Q

Multicellular Exocrine Glands: * The deeper cells within the connective tissue are

A

secretory

*However, cells lining the duct may also produce secretion

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22
Q

Multicellular Exocrine Glands: how is secretion discharged

A

Secretion is discharged from the cell surface into the duct, and then to the epithelial surface

23
Q

what are the 2 classifications of Multicellular Exocrine Glands based on their morphology

A
  • duct system
  • secretory end-pieces
24
Q

the 3 types of duct system

(multicellular exocrine glands)

A
  • Simple; single, unbranched duct (may be coiled)
  • Simple branched; two or more secretory areas empty into a common duct
  • Compound; branched duct system
25
3 types of secretory end pieces (multicellular exocrine glands)
* Tubular * Alveolar (acinar): rounded cluster of cells * Tubuloalveolar: tubular region ending in a rounded alveolus
26
what kind of glands are intestinal glands
simple tubular
27
what kind of glands are stomach (gastric) glands
simple branched tubular
28
what kind of glands are sebaceous glands
simple branched alveolar
29
what kind of glands are duodenal glands
compound tubular
30
what kind of glands are mammary glands
compound alveolar
31
what kind of glands are salivary glands
compound tubuloalveolar
32
in compound glands: secretory portions form ____ which may cluster into _____ separated by collagenous connective tissue
lobules lobes
33
for compound glands: Nerves, blood and lymph vessels enter via
connective tissue septae
34
Duct system begins within the lobules as ______ --> ______ --> ______ --> ______
intercalated ducts → intralobular (striated) duct → intralobar duct → excretory duct
35
compound glands: intercalated ducts → intralobular (striated) duct→ intralobar duct → excretory duct out of these which may modify the secretion
intralobular ducts
36
what kind of ducts are exocrine pancreas glands
compound alveolar
37
Mucous glands
* mucin * thick, sticky, glycoprotein
38
serous glands
* watery * enzymes
39
mixed glands
* contain more than one cell type * produce both mucous & serous secretions
40
most glands secrete how often
at a low level continuously
41
rate of secretion can be modulated by what
hormones, autonomic innervation or a combination of both
42
In glands with alveoli _____ contract to squeeze secretion into the ducts
contractile myoepithelial cells
43
in endocrine glands Connection with surface epithelium
is lost
44
where do endocrine glands secrete their products
Secrete products directly into blood or lymph transported throughout the body to target organ or tissue
45
are endocrine glands vascularized
yes, Well vascularised
46
endocrine secretions are
hormones such as * proteins * steroids
47
endocrine glands are adapted for
storing and releasing products as required
48
storage in endocrine glands is usually
intracellular *however, in thyroid stored in extracellular follicles
49
what kind of secretion do endocrines usually have
merocrine secretion
50
endocrine glands often form
cords or clumps
51
pancreas glands
exocrine and endocrine glands
52
islets of langerhands
endocrine glands in pancreas
53
in thyroid endocrine cells are arranged
into follicles surrounding a mass of secretory product (colloid; thyroglobulin)