gland secretions Flashcards
Secretion involves 3 distinct cellular activities:
- uptake of simple materials from the extracellular fluid
- processing of these within the cell: produce a more complex product
- release, or transport, of these products
what is excretion
which is the removal of waste products
can all cells secrete
yes
two functional types of glands
- Exocrine: release secretory products onto surface epithelium via
a duct - eg sweat glands, salivary glands
- Endocrine: no duct connecting secretory portion to surface epithelium, secrete products directly into blood or lymph (hormones)
- eg pancreas, thyroid gland
what forms multicellular exocrine and endocrine galnds
epithelial sheets
3 modes of secretion in exocrine glands
- Merocrine (eccrine)
- Apocrine
- Holocrine
merocrine (eccrine) secretion
(exocrine)
- vesicles are released via exocytosis when the vesicle
membranes fuse with the cell membrane - most common form of secretion
- e.g. some sweat glands, salivary glands
what is the most common form of secretion
Merocrine (eccrine)
Apocrine secretion
(exocrine)
- secretory vesicles accumulate at the apical portion of cell
- mass of cytoplasm and vesicles is then pinched off
- e.g. mammary gland, some sweat glands
holocrine secretion
(exocrine)
- secretory products accumulate and the cell ruptures
- death of cell
- e.g. sebaceous glands
A further classification of glands is based on structure:
unicellular and multicellular
unicellular glandular structure
- goblet cells of digestive & respiratory tracts
- the only type of unicellular gland
- secrete mucin –> mucous
most glands are multi or uni cellular
multicellular
goblet cells are found where
amongst columnar cells of epithelium
* digestive tract
* respiratory tract
in goblet cells there is Expanded apical portion (theca) contains
mucigen droplets
in goblet cells mucigen released by ____ secretion
merocrine
what makes up mucous
mucigen + H2O
describe nucleus in goblet cells
basal nucleus
describe cytoplasm in goblet cells
- Basophilic cytoplasm
- rER & free ribosomes
Multicellular Exocrine Glands: Secretions discharged onto epithelial surface via
ducts
Multicellular Exocrine Glands: * The deeper cells within the connective tissue are
secretory
*However, cells lining the duct may also produce secretion