cytoskeleton Flashcards

1
Q

cytoskeleton is a network of

A

fibers
cell’s internal skeleton

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2
Q

animal cells lack a

A

cell wall

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3
Q

cytoskeleton function

A
  • maintenance of cell shape; resists compression and torsion
  • organization of structures within the cell
  • organization of processes within the cell; division, movement
  • cell motility; cilia, flagella, pseudopodia
  • contraction of muscle cells
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4
Q

cytoskeleton consists of 3 types of fibers;

A
  • actin; microfilaments
  • tubulin; microtubules
  • intermediate filaments
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5
Q

what is most abundant intracellular protein

A

actin

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6
Q

actin is organized into

A

microfilaments
solid rods composed of globular actin proteins (subunits) organized into 2 intertwined strands

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7
Q

actin is dispersed throughout the cytoplasm but forms a dense meshwork immediately beneath the

A

plasma membrane

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8
Q

what determines and maintains the cell’s shape

A

actin

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9
Q

actin provides mechanical strength by

A

resisting tensive forces

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10
Q

actin in association w myosin filaments forms contractile structures such as

A
  • muscle cells (sarcomeres)
  • cleavage furrow of dividing cells
  • pseudopodia
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11
Q

bundles of ___ microfilaments make up the core of microvilli

A

actin

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12
Q

tubulin is organized into

A

microtubules
hollow tubes composed of 13 columns of tubulin proteins with alpha and beta-tubulin protein subunits

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13
Q

where is tubulin

A

distributed throughout cytoplasm

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14
Q

tubulin functions to maintain cell shape via

A

compression resisting girders that radiate from centrosome

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15
Q

tubulin acts as tracks which organelles can move such as

A

secretory vesicles from golgi to plasma membrane

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16
Q

tubulin forms centrioles

A
  • located within centrosome
  • 9 sets of microtubule triplets
  • involved in cell division (mitosis)
17
Q

during mitosis; centrioles

A
  • move to opposite ends of the cell, microtubules extend from one centriole to the other: spindle
  • daughter chromosomes pulled towards each centriole
18
Q

_____ also present in cilia and flagella

A

microtubules

19
Q

what is the only flagellated animal cell

A

sperm

20
Q

both cilia and flagella have a _____ microtubule arrangement and at the base is a

A

9+2
basal body = centriole

21
Q

intermediate filaments are

A

fibrous proteins that are coiled to form thick cables

22
Q

intermediate filaments consist of structurally related proteins including

A

keraitns, vimentin, demsin, neurofilaments

23
Q

where are intermediate filaments

A

distributed throughout cell

24
Q

intermediate filaments provide maintenance of cell shape by being

A

tension bearing, anchored to cell membrane

25
Q

nucleus is enclosed within a cage of

A

intermediate filaments

26
Q

5 major classes of intermediate filaments

A

1) keratin: skin epithelial cells, forms desmosomes
2) vimentin; epithelial cells, neural cells
3) desmin; muscle cells
4) glial filaments; glial cells
5) neurofilaments; neurons

27
Q

Which of the following statements about the cytoskeleton is INCORRECT?

A.
Actin is dispersed throughout the cytoplasm but forms a dense meshwork beneath the plasma membrane, where it provides mechanical strength by resisting tensive forces

B.
Intermediate filaments anchor the nucleus in its characteristic position for each cell type and also provide mechanical strength to microvilli

C.
Actin is a major component of sarcomeres, the contractile ring associated with the cleavage furrow of dividing cells, and the pseudopodia of amoebae, macrophages, and neutrophils

D.
Tubulin microtubules radiate from the centrosome, forming the tracks along which secretory vesicles travel when moving from the Golgi apparatus to the plasma membrane; tubulin is also organised into centrioles

A

Intermediate filaments anchor the nucleus in its characteristic position for each cell type and also provide mechanical strength to microvilli

28
Q

Which of the following statements about the cytoskeleton is INCORRECT?

A.
Actin is concentrated beneath the plasma membrane, where it provides mechanical strength by resisting tensive forces; it also supports the structure of microvilli

B.
Intermediate filaments are responsible for the maintenance of cell shape and anchoring of the nucleus, and are a component of desmosomes

C.
Actin forms the contractile ring associated with the cleavage furrow of dividing cells, and the pseudopodia of amoebae, macrophages, and neutrophils

D.
Tubulin microtubules form centrioles, cilia, and flagella, which consist of nine sets of microtubule doublets plus a central pair (i.e., 9 + 2 arrangement)

A

D.
Tubulin microtubules form centrioles, cilia, and flagella, which consist of nine sets of microtubule doublets plus a central pair (i.e., 9 + 2 arrangement)