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Pharmacology > GIT - Antiemetics, Antidiarrheal, Laxative And Purgative > Flashcards

GIT - Antiemetics, Antidiarrheal, Laxative And Purgative Flashcards

1
Q

Ach Blockers used for the prophylaxis of Motion sickness

A

Hyoscine (Scopolamine)

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2
Q

Antihistaminic drugs used to stop Vomiting

A

Promethazine
Doxylamine

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2
Q

Antihistaminic drugs used to stop Vomiting

A

Promethazine
Doxylamine

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3
Q

DOC in Morning sickness

A

Doxylamine + Pyridoxine

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4
Q

5-HT3 Blockers used as Antiemetics

A

Ondansetron
Granisetron
Tropisetron
Dolasetron
Palonosetron

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5
Q

5-HT3 Blockers are DOC in

A

Chemotherapy induced Vomiting
Radiotherapy induced
Postoperative Vomiting

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6
Q

5-HT3 Blockers are DOC in

A

Chemotherapy induced Vomiting
Radiotherapy induced
Postoperative Vomiting

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7
Q

Substance P (Neurokinin) Antagonist

A

Aprepitant
Fosaprepitant
Rolapitant
Netupitant

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7
Q

Substance P (Neurokinin) Antagonist

A

Aprepitant
Fosaprepitant
Rolapitant
Netupitant

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8
Q

Neurokinin Antagonist are DOC in

A

Delayed vomiting due to Chemotherapy

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8
Q

Neurokinin Antagonist are DOC in

A

Delayed vomiting due to Chemotherapy

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9
Q

Dopamine D2 blockers

A

Metoclopramide
Domperidone

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9
Q

Dopamine D2 blockers

A

Metoclopramide
Domperidone

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10
Q

Domperidone

A

Can’t cross BBB
No Extra pyramidal Symptoms

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11
Q

Metoclopramide

A

Can cross BBB
Can cause Extra pyramidal Symptoms

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12
Q

Metoclopramide

A

Can cross BBB
Can cause Extra pyramidal Symptoms

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13
Q

DOC in Levodopa induced Vomiting

A

Domperidone
Both can be used

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13
Q

DOC in Levodopa induced Vomiting

A

Domperidone
Both can be used

14
Q

New formula of ORS

A

NaCl - to replace electrolytes
KCl
Trisodium citrate - Stops acidosis
Glucose - helps in Absorption of Na

14
Q

New formula of ORS

A

NaCl - to replace electrolytes
KCl
Trisodium citrate - Stops acidosis
Glucose - helps in Absorption of Na

15
Q

Sodium and Glucose osmolarity in ORS

15
Q

Sodium and Glucose osmolarity in ORS

16
Q

Total Osmolarity of ORS

17
Q

Total Osmolarity of ORS

18
Q

Drugs used in Infection Induced Diarrhea

A

Amoebic - Metronidazole
Bacterial - Fluoroquinolones

18
Q

Drugs used in Infection Induced Diarrhea

A

Amoebic - Metronidazole
Bacterial - Fluoroquinolones

19
Q

Antidiarrheal drug used in Carcinoid syndrome and Vipoma

A

Octreotide - long acting Somatostatin

20
Q

Antidiarrheal only indicated for Non-infective Diarrhea

A

Loperamide
Diphenoxylate

20
Q

Antidiarrheal only indicated for Non-infective Diarrhea

A

Loperamide
Diphenoxylate

21
Q

Enkephalins are

A

Endogenous opioids
Decreases or stops secretion in GIT
Metaboized by Enkephalinase enzyme

22
Q

Drug which inhibits Enkephalinase enzyme

A

Racecadotril

22
Q

Drug which inhibits Enkephalinase enzyme

A

Racecadotril

23
Q

Types of Inflammatory Bowel disease

A

Ulcerative colitis
Crohn’s disease

24
Q

Types of Inflammatory Bowel disease

A

Ulcerative colitis
Crohn’s disease

25
Q

Drug used in Ulcerative colitis

A

5-Amino salicylic acid (5-ASA) - Powerful antiinflammatory drug

26
Q

5-ASA + Sulfapyridine

A

Sulfalsalzine

27
Q

5-ASA + Sulfapyridine

A

Sulfalsalzine

28
Q

5-ASA + 5-ASA

A

Olsalazine

28
Q

5-ASA + 5-ASA

A

Olsalazine

29
Q

5-ASA with pH sensitive covering

A

Mesalamine

30
Q

5-ASA with pH sensitive covering

A

Mesalamine

31
Q

DOC in Crohn’s disease

32
Q

Drugs used in Steroid resistant Crohn’s disease

A

TNF - Alpha blocker
A - Adalimumab
C - Certolizumab
E - Etanercept
IN - Infliximab
GOLI - Golimumab

32
Q

Drugs used in Steroid resistant Crohn’s disease

A

TNF - Alpha blocker
A - Adalimumab
C - Certolizumab
E - Etanercept
IN - Infliximab
GOLI - Golimumab

Pharmacology (14 decks)

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