GIT - Antiemetics, Antidiarrheal, Laxative And Purgative

Question 1

Ach Blockers used for the prophylaxis of Motion sickness

Answer 1

Hyoscine (Scopolamine)

Question 2

Antihistaminic drugs used to stop Vomiting

Answer 2

Promethazine
Doxylamine

Question 2

Antihistaminic drugs used to stop Vomiting

Answer 2

Promethazine
Doxylamine

Question 3

DOC in Morning sickness

Answer 3

Doxylamine + Pyridoxine

Question 4

5-HT3 Blockers used as Antiemetics

Answer 4

Ondansetron
Granisetron
Tropisetron
Dolasetron
Palonosetron

Question 5

5-HT3 Blockers are DOC in

Answer 5

Chemotherapy induced Vomiting
Radiotherapy induced
Postoperative Vomiting

Question 6

5-HT3 Blockers are DOC in

Answer 6

Chemotherapy induced Vomiting
Radiotherapy induced
Postoperative Vomiting

Question 7

Substance P (Neurokinin) Antagonist

Answer 7

Aprepitant
Fosaprepitant
Rolapitant
Netupitant

Question 7

Substance P (Neurokinin) Antagonist

Answer 7

Aprepitant
Fosaprepitant
Rolapitant
Netupitant

Question 8

Neurokinin Antagonist are DOC in

Answer 8

Delayed vomiting due to Chemotherapy

Question 8

Neurokinin Antagonist are DOC in

Answer 8

Delayed vomiting due to Chemotherapy

Question 9

Dopamine D2 blockers

Answer 9

Metoclopramide
Domperidone

Question 9

Dopamine D2 blockers

Answer 9

Metoclopramide
Domperidone

Question 10

Domperidone

Answer 10

Can’t cross BBB
No Extra pyramidal Symptoms

Question 11

Metoclopramide

Answer 11

Can cross BBB
Can cause Extra pyramidal Symptoms

Question 12

Metoclopramide

Answer 12

Can cross BBB
Can cause Extra pyramidal Symptoms

Question 13

DOC in Levodopa induced Vomiting

Answer 13

Domperidone
Both can be used

Question 13

DOC in Levodopa induced Vomiting

Answer 13

Domperidone
Both can be used

Question 14

New formula of ORS

Answer 14

NaCl - to replace electrolytes
KCl
Trisodium citrate - Stops acidosis
Glucose - helps in Absorption of Na

Question 14

New formula of ORS

Answer 14

NaCl - to replace electrolytes
KCl
Trisodium citrate - Stops acidosis
Glucose - helps in Absorption of Na

Question 15

Sodium and Glucose osmolarity in ORS

Answer 15

75meq/L

Question 15

Sodium and Glucose osmolarity in ORS

Answer 15

75meq/L

Question 16

Total Osmolarity of ORS

Answer 16

245meq/L

Question 17

Total Osmolarity of ORS

Answer 17

245meq/L

Question 18

Drugs used in Infection Induced Diarrhea

Answer 18

Amoebic - Metronidazole Bacterial - Fluoroquinolones

Question 18

Drugs used in Infection Induced Diarrhea

Answer 18

Amoebic - Metronidazole Bacterial - Fluoroquinolones

Question 19

Antidiarrheal drug used in Carcinoid syndrome and Vipoma

Answer 19

Octreotide - long acting Somatostatin

Question 20

Antidiarrheal only indicated for Non-infective Diarrhea

Answer 20

Loperamide Diphenoxylate

Question 20

Antidiarrheal only indicated for Non-infective Diarrhea

Answer 20

Loperamide Diphenoxylate

Question 21

Enkephalins are

Answer 21

Endogenous opioids Decreases or stops secretion in GIT Metaboized by Enkephalinase enzyme

Question 22

Drug which inhibits Enkephalinase enzyme

Answer 22

Racecadotril

Question 22

Drug which inhibits Enkephalinase enzyme

Answer 22

Racecadotril

Question 23

Types of Inflammatory Bowel disease

Answer 23

Ulcerative colitis Crohn's disease

Question 24

Types of Inflammatory Bowel disease

Answer 24

Ulcerative colitis Crohn's disease

Question 25

Drug used in Ulcerative colitis

Answer 25

5-Amino salicylic acid (5-ASA) - Powerful antiinflammatory drug

Question 26

5-ASA + Sulfapyridine

Answer 26

Sulfalsalzine

Question 27

5-ASA + Sulfapyridine

Answer 27

Sulfalsalzine

Question 28

5-ASA + 5-ASA

Answer 28

Olsalazine

Question 28

5-ASA + 5-ASA

Answer 28

Olsalazine

Question 29

5-ASA with pH sensitive covering

Answer 29

Mesalamine

Question 30

5-ASA with pH sensitive covering

Answer 30

Mesalamine

Question 31

DOC in Crohn's disease

Answer 31

Steroids

Question 32

Drugs used in Steroid resistant Crohn's disease

Answer 32

TNF - Alpha blocker A - Adalimumab C - Certolizumab E - Etanercept IN - Infliximab GOLI - Golimumab

Question 32

Drugs used in Steroid resistant Crohn's disease

Answer 32

TNF - Alpha blocker A - Adalimumab C - Certolizumab E - Etanercept IN - Infliximab GOLI - Golimumab