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Pharmacology > CVS - Pulmonary HTN And Shock > Flashcards

CVS - Pulmonary HTN And Shock Flashcards

1
Q

In Pulmonary HTN which group of drug is given for iv Vasodilator testing

A

iv Calcium channel blockers

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2
Q

DOC if iv CCB is effective in Pulmonary HTN

A

Oral Calcium channel blockers (5%)

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3
Q

DOC if iv CCB not effective in Pulmonary HTN

A

Endothelin antagonist

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4
Q

Endothelin antagonist drugs include

A

Bosentan
Ambresentan
Macicentan

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5
Q

Phosphodiesterase inhibitors used in Pulmonary HTN

A

Sildenafil
Tadalfil - longest acting
Also used in Impotency

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5
Q

Phosphodiesterase inhibitors used in Pulmonary HTN

A

Sildenafil
Tadalfil - longest acting
Also used in Impotency

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6
Q

Prostaglandins PGI2 nd E2 include which drugs

A

Iloprost
Epoprostenol
Trepnestinil
Most effective
Cannot be given orally

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7
Q

Which drug is selective Non-injectable PGI2 antagonist

A

Selexipag - Oral

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8
Q

Guanylate cyclase agonist used in Pulmonary HTN

A

Riociguat

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8
Q

Guanylate cyclase agonist used in Pulmonary HTN

A

Riociguat

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9
Q

Most commonly used drug in Pulmonary HTN

A

Warfarin - because there is high risk of Thromboembolism

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10
Q

Shock means

A

Decreased tissue perfusion

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10
Q

Shock means

A

Decreased tissue perfusion

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11
Q

Periphery will be cold in which Shock

A

Cardiogenic shock
Hypovolemic shock

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11
Q

Periphery will be cold in which Shock

A

Cardiogenic shock
Hypovolemic shock

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12
Q

Periphery will be warm in which Shock

A

In Distributive Shock due to Vasodilation
Hypoadrenal Shock
Septic shock
Neurogenic shock
Anaphylactic shock

13
Q

Secondary shock is due to

A

Vasoconstriction

14
Q

Treatment of Shock

A

CAB - Chest compressions, breathing and airway
Fluid replacement - Ringer lactate or Normal saline
Vasopressors

15
Q

Vasopressors used in Septic shock

A

Nor adrenaline - DOC
Dopamine
Phenylephrine

16
Q

Vasopressors used in Cardiogenic shock

A

Nor adrenaline
Dopamine

17
Q

Specific treatment in Septic shock

A

Antimicrobial agents

17
Q

Specific treatment in Septic shock

A

Antimicrobial agents

18
Q

DOC In Anaphylactic shock

A

Adrenaline im 1:1000

18
Q

DOC In Anaphylactic shock

A

Adrenaline im 1:1000

19
Q

DOC in Hypoadrenal Shock

A

Steroids

19
Q

DOC in Hypoadrenal Shock

A

Steroids

20
Q

Treatment of Secondary shock

A

Vasodilators

20
Q

Treatment of Secondary shock

A

Vasodilators

Pharmacology (14 decks)

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