Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI/Liver: Pharmacology > GI tumor treatment: Adverse effects > Flashcards

GI tumor treatment: Adverse effects Flashcards

This just includes the bolded AEs

1
Q

What are the adverse effects associated with brevacizumab?

A

Bleeding
GI perforation
Wound dihiscence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the adverse effects associated with Capecitabine?

A

Dihydropyrimidine dehydrogenase deficiency prevents metabolic activation

Contraindicated in renal dysfunction
Adverse CV events (interacts with coumarin)
Neuro toxicity
Hematotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the adverse effects associated with Cetuximab?

A

Cardiac arrest
respiratory arrest
sudden death

Acneiform rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the adverse effects associated with Cisplatin?

A

Nephrotoxicity
Myelosuppression
Ototoxicity
Platinum hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the adverse effects associated with Docetaxel?

A

Increased treatment related mortality in NSCLC
Edema
Contraindicated in hepatic disease
Neutropenia (dose limiting toxicity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the adverse effects associated with Erlotinib?

A 
GI toxicity (N/V, diarrhea)
Prolonged bleeding
increased LFTs
Ocular toxicity
interstitial lung disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the adverse effects associated with flourouracil?

A

Severe hematotoxicity

DPD deficiency enhances neurotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the adverse effects associated with Gemcitabine?

A

Infection
Neuropathy
arthralgia
GI toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the adverse effects associated with Doxorubicin?

A

Bone marrow suppression, secondary malignancy
heart dz
Hepatic dz
extravasational necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the adverse effects associated with Glutamic acid?

A

No serious side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the adverse effects associated with Imatinib?

A

GI toxicity
CHF
neuro toxicity
Fluid retention/edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the adverse effects associated with IFN-alpha?

A

Neuro-psychiatric events

Flu-like symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the adverse effects associated with Irinotecan?

A

Bone marrow suppression

diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the adverse effects associated with leucovorin?

A

Diarrhea

dehydration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the adverse effects associated with Methysergide?

A

Vasoconstrictor of large and small arteries used in migraine therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the adverse effects associated with Mitomycin?

A

Bone marrow suppression

HUS

17
Q

What are the adverse effects associated with Octreotide?

A

monitor blood glucose
inhibits insulin and glucagon
Dose related diarrhea

18
Q

What are the adverse effects associated with Oxaliplatin?

A

Dose limiting neurotoxicity
Thrombocytopenia (with FU and leucovorin)
GI toxicity
stomatitis

19
Q

What are the adverse effects associated with Sorafenib?

A

Hand and foot skin rxn in first 6 weeks of treatment

20
Q

What are the adverse effects associated with Sunitinib?

A

Thrombocytopenia
QT prolongation
Rare GI perforation

21
Q

What are the adverse effects associated with Trastuzumab?

A 
LVEF dysfunction and cardiomyopathy
Infusion rxn (anaphylaxis, angioedema)
Pulmonary toxicity.

GI/Liver: Pharmacology (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions